Assessing bone mineral density and cortical geometry using high-resolution peripheral quantitative computed tomography in pediatric survivors of high-risk neuroblastoma with severe growth failure
Sonia Gera
1
,
Michelle Guo
2
,
Yang Xie
1
,
Netanya Pollock
1
,
Minkeun Song
1
,
David R. Weber
1, 3
,
Michelle Denburg
1, 3
,
Babette Zemel
1, 3
,
Sogol Mostoufi-Moab
1, 3
Publication type: Journal Article
Publication date: 2025-06-01
scimago Q1
wos Q2
SJR: 1.250
CiteScore: 8.2
Impact factor: 3.6
ISSN: 87563282, 18732763
Abstract
IntroductionSurvival of children with high-risk neuroblastoma (HR-NBL) has increased with multimodal therapy. cis-Retinoic acid (cis-RA), cornerstone of HR-NBL therapy, can cause osteoporosis and premature physeal closure. This study utilized high-resolution peripheral quantitative computed tomography (HR-pQCT), for 3D measures of volumetric bone mineral density (BMD) and microarchitecture, to assess impact of HR-NBL therapy on skeletal structure.
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Gera S. et al. Assessing bone mineral density and cortical geometry using high-resolution peripheral quantitative computed tomography in pediatric survivors of high-risk neuroblastoma with severe growth failure // Bone. 2025. Vol. 195. p. 117468.
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Gera S., Guo M., Xie Y., Pollock N., Song M., Weber D. R., Denburg M., Zemel B., Mostoufi-Moab S. Assessing bone mineral density and cortical geometry using high-resolution peripheral quantitative computed tomography in pediatric survivors of high-risk neuroblastoma with severe growth failure // Bone. 2025. Vol. 195. p. 117468.
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TY - JOUR
DO - 10.1016/j.bone.2025.117468
UR - https://linkinghub.elsevier.com/retrieve/pii/S8756328225000808
TI - Assessing bone mineral density and cortical geometry using high-resolution peripheral quantitative computed tomography in pediatric survivors of high-risk neuroblastoma with severe growth failure
T2 - Bone
AU - Gera, Sonia
AU - Guo, Michelle
AU - Xie, Yang
AU - Pollock, Netanya
AU - Song, Minkeun
AU - Weber, David R.
AU - Denburg, Michelle
AU - Zemel, Babette
AU - Mostoufi-Moab, Sogol
PY - 2025
DA - 2025/06/01
PB - Elsevier
SP - 117468
VL - 195
SN - 8756-3282
SN - 1873-2763
ER -
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@article{2025_Gera,
author = {Sonia Gera and Michelle Guo and Yang Xie and Netanya Pollock and Minkeun Song and David R. Weber and Michelle Denburg and Babette Zemel and Sogol Mostoufi-Moab},
title = {Assessing bone mineral density and cortical geometry using high-resolution peripheral quantitative computed tomography in pediatric survivors of high-risk neuroblastoma with severe growth failure},
journal = {Bone},
year = {2025},
volume = {195},
publisher = {Elsevier},
month = {jun},
url = {https://linkinghub.elsevier.com/retrieve/pii/S8756328225000808},
pages = {117468},
doi = {10.1016/j.bone.2025.117468}
}
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