том 25 издание 1 страницы 115-119

Antigen presentation by Langerhans cells

Тип публикацииJournal Article
Дата публикации2013-03-01
scimago Q1
wos Q1
БС1
SJR2.740
CiteScore13.2
Impact factor5.8
ISSN09527915, 18790372
Immunology
Immunology and Allergy
Краткое описание
► CD103+ dDC, not LC are responsible for cross-priming. ► LC promote Th17 in response to extracellular pathogens. ► LC promote Th2 in response to epicutaneous immunization. ► Presentation by LC may result in T cell anergy/deletion. Langerhans cells and other skin-resident dendritic cells (DC) are required for the development of cutaneous adaptive immune responses. In vivo experiments using mice with selective DC-subset deficiencies and ex vivo experiments using isolated DC suggests that each subset makes a unique contribution to the adaptive response. This review focuses on the functional outcome of antigen presentation by Langerhans cells. Special attention is given to their ability to promote CD4 T cell differentiation in a variety of inflammatory contexts and whether this subset has the capacity to cross-prime CD8 T cells.
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ГОСТ |
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Igyarto B. Z., Kaplan D. H. Antigen presentation by Langerhans cells // Current Opinion in Immunology. 2013. Vol. 25. No. 1. pp. 115-119.
ГОСТ со всеми авторами (до 50) Скопировать
Igyarto B. Z., Kaplan D. H. Antigen presentation by Langerhans cells // Current Opinion in Immunology. 2013. Vol. 25. No. 1. pp. 115-119.
RIS |
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TY - JOUR
DO - 10.1016/j.coi.2012.11.007
UR - https://doi.org/10.1016/j.coi.2012.11.007
TI - Antigen presentation by Langerhans cells
T2 - Current Opinion in Immunology
AU - Igyarto, Botond Z.
AU - Kaplan, Daniel H.
PY - 2013
DA - 2013/03/01
PB - Elsevier
SP - 115-119
IS - 1
VL - 25
PMID - 23246038
SN - 0952-7915
SN - 1879-0372
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2013_Igyarto,
author = {Botond Z. Igyarto and Daniel H. Kaplan},
title = {Antigen presentation by Langerhans cells},
journal = {Current Opinion in Immunology},
year = {2013},
volume = {25},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016/j.coi.2012.11.007},
number = {1},
pages = {115--119},
doi = {10.1016/j.coi.2012.11.007}
}
MLA
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Igyarto, Botond Z., and Daniel H. Kaplan. “Antigen presentation by Langerhans cells.” Current Opinion in Immunology, vol. 25, no. 1, Mar. 2013, pp. 115-119. https://doi.org/10.1016/j.coi.2012.11.007.