Open Access
Open access
Elsevier
Current Problems in Cancer Case Reports
,  volume 9 ,  pages 100213

Diagnosing primary pancreatic acinar cell carcinoma – Clinical correlation of radiological/molecular imaging, histopathologic features and whole genome/transcriptome profiling, and review of the literature

Kevin Tran 1, 2
, 
Owen Prall 3
, 
C. Mitchell 3
, 
Angela Chou 4, 5
, 
Armaan Gill 4, 5
, 
Sean Grimmond 6
, 
Grace Kong 7
, 
Gareth Kiernan 1
, 
Cristina Torche 1, 8
, 
Lara Lipton 9, 10, 11
, 
Benjamin N.J. Thomson 2, 12, 13
, 
Hyun Soo Ko 7, 14
1
 
2
 
3
 
4
 
5
 
6
 
7
 
8
 
Department of Imaging, Guillermo Grant Benavente Hospital, Concepcion, Chile | 
9
 
Department of Medical Oncology, Cabrini Hospital, Melbourne, VIC, Australia | 
10
 
11
 
12
 
13
 
14
 
Publication type: Journal Article
Publication date: 2023-03-01
Elsevier
scimago Q4
wos Q4
SJR: 0.160
CiteScore: 0.6
Impact factor: 0.2
ISSN: 26666219
Oncology
Abstract
Pancreatic acinar cell carcinoma (ACC) is a rare pancreatic neoplasm, often eluding clinicians because of the lack of diagnosis awareness and expert knowledge regarding clinical, radiological and pathological characteristics of ACC. Main differential diagnoses include pancreatic ductal adenocarcinoma (PDAC) and pancreatic neuroendocrine tumor (PNET) and accurate diagnosis is crucial to ensure optimal treatment and outcomes. This case of a 58-year old male illustrates the correlation between clinical, imaging, molecular histopathological and whole genome and transcriptome profiling that was required to diagnose and guide treatment of this complex pancreatic ACC.
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GOST Copy
Tran K. et al. Diagnosing primary pancreatic acinar cell carcinoma – Clinical correlation of radiological/molecular imaging, histopathologic features and whole genome/transcriptome profiling, and review of the literature // Current Problems in Cancer Case Reports. 2023. Vol. 9. p. 100213.
GOST all authors (up to 50) Copy
Tran K., Prall O., Mitchell C., Chou A., Gill A., Grimmond S., Kong G., Kiernan G., Torche C., Lipton L., Thomson B. N., Ko H. S. Diagnosing primary pancreatic acinar cell carcinoma – Clinical correlation of radiological/molecular imaging, histopathologic features and whole genome/transcriptome profiling, and review of the literature // Current Problems in Cancer Case Reports. 2023. Vol. 9. p. 100213.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.cpccr.2022.100213
UR - https://doi.org/10.1016/j.cpccr.2022.100213
TI - Diagnosing primary pancreatic acinar cell carcinoma – Clinical correlation of radiological/molecular imaging, histopathologic features and whole genome/transcriptome profiling, and review of the literature
T2 - Current Problems in Cancer Case Reports
AU - Tran, Kevin
AU - Prall, Owen
AU - Mitchell, C.
AU - Chou, Angela
AU - Gill, Armaan
AU - Grimmond, Sean
AU - Kong, Grace
AU - Kiernan, Gareth
AU - Torche, Cristina
AU - Lipton, Lara
AU - Thomson, Benjamin N.J.
AU - Ko, Hyun Soo
PY - 2023
DA - 2023/03/01
PB - Elsevier
SP - 100213
VL - 9
SN - 2666-6219
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2023_Tran,
author = {Kevin Tran and Owen Prall and C. Mitchell and Angela Chou and Armaan Gill and Sean Grimmond and Grace Kong and Gareth Kiernan and Cristina Torche and Lara Lipton and Benjamin N.J. Thomson and Hyun Soo Ko},
title = {Diagnosing primary pancreatic acinar cell carcinoma – Clinical correlation of radiological/molecular imaging, histopathologic features and whole genome/transcriptome profiling, and review of the literature},
journal = {Current Problems in Cancer Case Reports},
year = {2023},
volume = {9},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016/j.cpccr.2022.100213},
pages = {100213},
doi = {10.1016/j.cpccr.2022.100213}
}