Can brain games help smokers quit?: Results of a randomized clinical trial
James Loughead
1
,
Mary Falcone
1
,
E Paul Wileyto
2
,
Benjamin Albelda
1
,
Janet Audrain-McGovern
1
,
Wen Cao
1
,
Matthew M. Kurtz
3
,
Ruben C. Gur
4
,
C Lerman
1
1
Department of Psychiatry, University of PA, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, United States
|
2
Department of Biostatistics and Epidemiology, University of PA, Room 619, Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, United States.
|
3
4
Department of Psychiatry, Hospital of the University of PA, 10th Floor Gates Building, 3400 Spruce Street, Philadelphia, PA 19104, United States.
|
Publication type: Journal Article
Publication date: 2016-11-01
scimago Q1
wos Q1
SJR: 1.657
CiteScore: 7.9
Impact factor: 3.6
ISSN: 03768716, 18790046
PubMed ID:
27635998
Pharmacology
Pharmacology (medical)
Psychiatry and Mental health
Toxicology
Abstract
Deficits in cognitive function are observed during nicotine withdrawal and present a challenge to successful smoking cessation. This clinical trial evaluated a cognitive exercise training (CT) program to improve smoking cessation rates.Adult treatment-seeking smokers (n=213) were randomized to receive nicotine patch therapy and 12 weeks of either computerized CT or computerized relaxation (control) training. Smoking status was biochemically verified at the end of treatment and 6-month follow-up.Quit rates did not differ by treatment arm at either time-point, nor were there effects on withdrawal symptoms or smoking urges. Reaction time for emotion recognition and verbal interference tasks showed improvement in the CT group. When including only successful quitters, improvements in recognition memory, verbal interference accuracy, and attention switching error rate were also observed in the CT group, while commission errors on the continuous performance task decreased in the control group.Despite modest changes in cognitive performance, these results do not support the efficacy of computerized cognitive training as an adjunctive therapy for smoking cessation.
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Total citations:
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Citations from 2024:
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(8.33%)
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GOST
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Loughead J. et al. Can brain games help smokers quit?: Results of a randomized clinical trial // Drug and Alcohol Dependence. 2016. Vol. 168. pp. 112-118.
GOST all authors (up to 50)
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Loughead J., Falcone M., Wileyto E. P., Albelda B., Audrain-McGovern J., Cao W., Kurtz M. M., Gur R. C., Lerman C. Can brain games help smokers quit?: Results of a randomized clinical trial // Drug and Alcohol Dependence. 2016. Vol. 168. pp. 112-118.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.drugalcdep.2016.08.621
UR - https://doi.org/10.1016/j.drugalcdep.2016.08.621
TI - Can brain games help smokers quit?: Results of a randomized clinical trial
T2 - Drug and Alcohol Dependence
AU - Loughead, James
AU - Falcone, Mary
AU - Wileyto, E Paul
AU - Albelda, Benjamin
AU - Audrain-McGovern, Janet
AU - Cao, Wen
AU - Kurtz, Matthew M.
AU - Gur, Ruben C.
AU - Lerman, C
PY - 2016
DA - 2016/11/01
PB - Elsevier
SP - 112-118
VL - 168
PMID - 27635998
SN - 0376-8716
SN - 1879-0046
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Loughead,
author = {James Loughead and Mary Falcone and E Paul Wileyto and Benjamin Albelda and Janet Audrain-McGovern and Wen Cao and Matthew M. Kurtz and Ruben C. Gur and C Lerman},
title = {Can brain games help smokers quit?: Results of a randomized clinical trial},
journal = {Drug and Alcohol Dependence},
year = {2016},
volume = {168},
publisher = {Elsevier},
month = {nov},
url = {https://doi.org/10.1016/j.drugalcdep.2016.08.621},
pages = {112--118},
doi = {10.1016/j.drugalcdep.2016.08.621}
}