Elsevier
Dyes and Pigments
,  volume 235 ,  pages 112599

Advances in Small-Molecule Fluorescent Probes for Cellular senescence Diagnosis and Therapy: A review

Chunhong Sui 1
1
 
College of Pharmacy, Jilin Medical University, 132013, Ji'lin, PR China | 
Publication type: Journal Article
Publication date: 2025-04-01
Elsevier
scimago Q2
wos Q1
SJR: 0.680
CiteScore: 8.5
Impact factor: 4.2
ISSN: 01437208, 18733743
Abstract
Cellular senescence is not only a key component of the natural aging process driven by multiple factors but is also closely linked to the development of age-related diseases such as Alzheimer's, cardiovascular diseases, and cancer. Investigating the application of small-molecule fluorescent probes for non-invasive monitoring and treatment of senescence-related diseases holds significant potential. Accurate detection of senescence biomarkers using these probes offers promising opportunities for early diagnosis. Thoughtful design of these probes with therapeutic capabilities may provide new strategies for disease intervention, potentially slowing the senescence process and addressing the challenges posed by a senescence population. In this review, we highlight recent advancements in the use of small-molecule fluorescent probes for detecting senescence biomarkers and exploring therapeutic strategies.
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Wang X. et al. Advances in Small-Molecule Fluorescent Probes for Cellular senescence Diagnosis and Therapy: A review // Dyes and Pigments. 2025. Vol. 235. p. 112599.
GOST all authors (up to 50) Copy
Sui C. Advances in Small-Molecule Fluorescent Probes for Cellular senescence Diagnosis and Therapy: A review // Dyes and Pigments. 2025. Vol. 235. p. 112599.
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RIS Copy
TY - JOUR
DO - 10.1016/j.dyepig.2024.112599
UR - https://linkinghub.elsevier.com/retrieve/pii/S0143720824006661
TI - Advances in Small-Molecule Fluorescent Probes for Cellular senescence Diagnosis and Therapy: A review
T2 - Dyes and Pigments
AU - Sui, Chunhong
PY - 2025
DA - 2025/04/01
PB - Elsevier
SP - 112599
VL - 235
SN - 0143-7208
SN - 1873-3743
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Wang,
author = {Chunhong Sui},
title = {Advances in Small-Molecule Fluorescent Probes for Cellular senescence Diagnosis and Therapy: A review},
journal = {Dyes and Pigments},
year = {2025},
volume = {235},
publisher = {Elsevier},
month = {apr},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0143720824006661},
pages = {112599},
doi = {10.1016/j.dyepig.2024.112599}
}