Elsevier
European Journal of Medicinal Chemistry
,  volume 275 ,  pages 116596

(+)-fenchol and (−)-isopinocampheol derivatives targeting the entry process of filoviruses

Anastasiya S. Sokolova 1
, 
Dmitry S. Baev 1, 2
, 
Ekaterina D. Mordvinova 3
, 
Olga I. Yarovaya 1
, 
N. V. Volkova 3
, 
Dmitriy N. Shcherbakov 3
, 
Alina A Okhina 1
, 
Artem Rogachev 1
, 
T. A. Shnaider 4
, 
Anastasiya S. Chvileva 5
, 
Tatyana V. Nikitina 6
, 
Tatyana G. Tolstikova 1
, 
Nariman F. Salakhutdinov 1
1
 
2
 
SRF SKIF, Koltsovo, Novosibirsk Oblast, 630559, Russian Federation | 
3
 
4
 
5
 
6
 
Publication type: Journal Article
Publication date: 2024-09-01
Elsevier
scimago Q1
wos Q1
SJR: 1.142
CiteScore: 11.3
Impact factor: 5.9
ISSN: 02235234, 17683254
Abstract
The increasing frequency of filovirus outbreaks in African countries has led to a pressing need for the development of effective antifilovirus agents. In continuation of our previous research on the antifilovirus activity of monoterpenoid derivatives, we synthesized a series of (+)-fenchol and (-)-isopinocampheol derivatives by varying the type of heterocycle and linker length. Derivatives with an N-alkylpiperazine cycle proved to be the most potent antiviral compounds, with half-maximal inhibitory concentration (IC
Found 
Found 

Top-30

Journals

1
Journal of Materials Research and Technology
Journal of Materials Research and Technology, 1, 50%
Journal of Materials Research and Technology
1 publication, 50%
South African Journal of Botany
South African Journal of Botany, 1, 50%
South African Journal of Botany
1 publication, 50%
1

Publishers

1
2
Elsevier
Elsevier, 2, 100%
Elsevier
2 publications, 100%
1
2
  • We do not take into account publications without a DOI.
  • Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
2
Share
Cite this
GOST |
Cite this
GOST Copy
Sokolova A. S. et al. (+)-fenchol and (−)-isopinocampheol derivatives targeting the entry process of filoviruses // European Journal of Medicinal Chemistry. 2024. Vol. 275. p. 116596.
GOST all authors (up to 50) Copy
Sokolova A. S., S. Baev D., Mordvinova E. D., Yarovaya O. I., Volkova N. V., Shcherbakov D. N., Okhina A. A., Rogachev A., Shnaider T. A., Chvileva A. S., Nikitina T. V., Tolstikova T. G., Salakhutdinov N. F. (+)-fenchol and (−)-isopinocampheol derivatives targeting the entry process of filoviruses // European Journal of Medicinal Chemistry. 2024. Vol. 275. p. 116596.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.ejmech.2024.116596
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196192293&origin=inward
TI - (+)-fenchol and (−)-isopinocampheol derivatives targeting the entry process of filoviruses
T2 - European Journal of Medicinal Chemistry
AU - Sokolova, Anastasiya S.
AU - S. Baev, Dmitry
AU - Mordvinova, Ekaterina D.
AU - Yarovaya, Olga I.
AU - Volkova, N. V.
AU - Shcherbakov, Dmitriy N.
AU - Okhina, Alina A
AU - Rogachev, Artem
AU - Shnaider, T. A.
AU - Chvileva, Anastasiya S.
AU - Nikitina, Tatyana V.
AU - Tolstikova, Tatyana G.
AU - Salakhutdinov, Nariman F.
PY - 2024
DA - 2024/09/01
PB - Elsevier
SP - 116596
VL - 275
PMID - 38889610
SN - 0223-5234
SN - 1768-3254
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2024_Sokolova,
author = {Anastasiya S. Sokolova and Dmitry S. Baev and Ekaterina D. Mordvinova and Olga I. Yarovaya and N. V. Volkova and Dmitriy N. Shcherbakov and Alina A Okhina and Artem Rogachev and T. A. Shnaider and Anastasiya S. Chvileva and Tatyana V. Nikitina and Tatyana G. Tolstikova and Nariman F. Salakhutdinov},
title = {(+)-fenchol and (−)-isopinocampheol derivatives targeting the entry process of filoviruses},
journal = {European Journal of Medicinal Chemistry},
year = {2024},
volume = {275},
publisher = {Elsevier},
month = {sep},
url = {https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85196192293&origin=inward},
pages = {116596},
doi = {10.1016/j.ejmech.2024.116596}
}