Phenolics from Leontopodium leontopodioides inhibiting nitric oxide production
Publication type: Journal Article
Publication date: 2012-07-01
scimago Q2
wos Q3
SJR: 0.537
CiteScore: 3.9
Impact factor: 2.6
ISSN: 0367326X, 18736971
PubMed ID:
22484093
Drug Discovery
General Medicine
Pharmacology
Abstract
Two new compounds, a neolignan (1), and a benzofuran derivative (2), along with 6 known compounds (3-8), were isolated from the aerial parts of Leontopodium leontopodioides. The structures of the new compounds were elucidated as (7R,8S)-3,5'-dimethoxy-4',7-epoxy-8,3'-neolignane-5,9,9'-triol (1) and (2R)-12-hydoxy-4-methoxy-tremeton (2) on the basis of their spectroscopic data, respectively. All of the isolates were evaluated for their effects on the inhibition of nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages and compounds 1 and 8 exhibited inhibitory activity with IC(50) values of 35.80 and 24.41 μM, respectively.
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Total citations:
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Citations from 2024:
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(12.5%)
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MLA
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GOST
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Li X. et al. Phenolics from Leontopodium leontopodioides inhibiting nitric oxide production // Fitoterapia. 2012. Vol. 83. No. 5. pp. 883-887.
GOST all authors (up to 50)
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Li X., Luo J., Wang X., Luo J., Wang J., Kong L. Phenolics from Leontopodium leontopodioides inhibiting nitric oxide production // Fitoterapia. 2012. Vol. 83. No. 5. pp. 883-887.
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RIS
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TY - JOUR
DO - 10.1016/j.fitote.2012.03.020
UR - https://doi.org/10.1016/j.fitote.2012.03.020
TI - Phenolics from Leontopodium leontopodioides inhibiting nitric oxide production
T2 - Fitoterapia
AU - Li, Xin
AU - Luo, Jian-Guang
AU - Wang, Xiao-Bing
AU - Luo, Jun
AU - Wang, Jun-Song
AU - Kong, Ling-Yi
PY - 2012
DA - 2012/07/01
PB - Elsevier
SP - 883-887
IS - 5
VL - 83
PMID - 22484093
SN - 0367-326X
SN - 1873-6971
ER -
Cite this
BibTex (up to 50 authors)
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@article{2012_Li,
author = {Xin Li and Jian-Guang Luo and Xiao-Bing Wang and Jun Luo and Jun-Song Wang and Ling-Yi Kong},
title = {Phenolics from Leontopodium leontopodioides inhibiting nitric oxide production},
journal = {Fitoterapia},
year = {2012},
volume = {83},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/j.fitote.2012.03.020},
number = {5},
pages = {883--887},
doi = {10.1016/j.fitote.2012.03.020}
}
Cite this
MLA
Copy
Li, Xin, et al. “Phenolics from Leontopodium leontopodioides inhibiting nitric oxide production.” Fitoterapia, vol. 83, no. 5, Jul. 2012, pp. 883-887. https://doi.org/10.1016/j.fitote.2012.03.020.