Isobenzofuranones from the aerial parts of Leontopodium leontopodioides (Wild.) Beauv.
Yuling Yang
1
,
Jingya Ruan
2
,
Chen Qiu
2
,
Li Jian
3
,
Yuanqiang Guo
1
,
Li-feng HAN
2
,
Tao Wang
2
Publication type: Journal Article
Publication date: 2018-01-01
scimago Q2
wos Q3
SJR: 0.537
CiteScore: 3.9
Impact factor: 2.6
ISSN: 0367326X, 18736971
PubMed ID:
29074227
Drug Discovery
General Medicine
Pharmacology
Abstract
A phytochemical investigation to obtain new triglyceride (TG) accumulation inhibitors resulted in the isolation of six new isobenzofuranones, leontopodiols A (1), B (2), leontopodiosides C (3), D (4), E (5), F (6), together with three known ones (7-9) from the aerial parts of Leontopodium leontopodioides (Willd.) Beauv. The structures of these isolates were identified by routine NMR experiments, optical rotation determination, electronic circular dichroism (ECD) calculation, along with chemical reaction. Moreover, compounds 1, 2, 5, and 7-9 displayed TG accumulation inhibitory effects on HepG2 cells.
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Total citations:
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Citations from 2024:
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(28.57%)
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GOST
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Zhang Y. et al. Isobenzofuranones from the aerial parts of Leontopodium leontopodioides (Wild.) Beauv. // Fitoterapia. 2018. Vol. 124. pp. 66-72.
GOST all authors (up to 50)
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Yang Y., Ruan J., Qiu C., Jian L., Guo Y., HAN L., Wang T. Isobenzofuranones from the aerial parts of Leontopodium leontopodioides (Wild.) Beauv. // Fitoterapia. 2018. Vol. 124. pp. 66-72.
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RIS
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TY - JOUR
DO - 10.1016/j.fitote.2017.10.019
UR - https://doi.org/10.1016/j.fitote.2017.10.019
TI - Isobenzofuranones from the aerial parts of Leontopodium leontopodioides (Wild.) Beauv.
T2 - Fitoterapia
AU - Yang, Yuling
AU - Ruan, Jingya
AU - Qiu, Chen
AU - Jian, Li
AU - Guo, Yuanqiang
AU - HAN, Li-feng
AU - Wang, Tao
PY - 2018
DA - 2018/01/01
PB - Elsevier
SP - 66-72
VL - 124
PMID - 29074227
SN - 0367-326X
SN - 1873-6971
ER -
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BibTex (up to 50 authors)
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@article{2018_Zhang,
author = {Yuling Yang and Jingya Ruan and Chen Qiu and Li Jian and Yuanqiang Guo and Li-feng HAN and Tao Wang},
title = {Isobenzofuranones from the aerial parts of Leontopodium leontopodioides (Wild.) Beauv.},
journal = {Fitoterapia},
year = {2018},
volume = {124},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.fitote.2017.10.019},
pages = {66--72},
doi = {10.1016/j.fitote.2017.10.019}
}