Food Chemistry, volume 301, pages 125247

Novel non-toxic high efficient antibacterial azido chitosan derivatives with potential application in food coatings

Kritchenkov Andreii S. ^{1, 2}

Egorov Anton R ¹

Kurasova Margarita N ³

Volkova Olga V ⁴

Meledina Tatyana V ⁴

Lipkan Nikita A ⁴

Tskhovrebov Alexander ⁵

Kurliuk Aleh V ⁶

Shakola Tatsiana V ⁶

Dysin Artem P. ⁴

Egorov Mikhail Yu ⁷

Savicheva Elizaveta A ⁸

Dos Santos Wesley Moreira ⁴

Hide authors affiliations Show authors affiliations: 8 affiliations

Institute of Macromolecular Compounds of the Russian Academy of Sciences, Bolshoi pr. VO 31, St. Petersburg 199004, Russian Federation |

Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, Moscow 117198, Russian Federation |

Peoples׳ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, Moscow 117198, Russian Federation. |

⁴

Saint-Petersburg National Research University of Information Technologies, Mechanics, and Optics, Kronverkskii pr. 49, St. Petersburg 197101, Russian Federation |

⁵

N. N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Kosygina Street 4, Building 1, Moscow 119991, Russian Federation |

⁶

Vitebsk State Medical University, Frunze av. 27, Vitebsk 210009, Belarus |

⁷

Peter the Great Saint Petersburg Polytechnic University, 29 Polytechnicheskaya Street, St. Petersburg, 195251, Russian Federation |

⁸

Max Planck Institute for Biophysical Chemistry, Am Fassberg 1, Göttingen, 37077, Germany |

Publication type: Journal Article

Publication date: 2019-12-01

Elsevier

Journal: Food Chemistry

Quartile SCImago

Quartile WOS

Impact factor: 8.8

ISSN: 03088146, 18737072

DOI: 10.1016/j.foodchem.2019.125247

Copy DOI

General Medicine

Analytical Chemistry

Food Science

Abstract

In this work, we developed a simple method for the preparation of N-(3-azido-2-hydroxypropyl)chitosan. We compared the antibacterial activity of N-(3-azido-2-hydroxypropyl)chitosans and previously synthesized N-(2-azidoethyl)chitosans. N-(3-azido-2-hydroxypropyl)chitosans possess higher antibacterial effect which is comparable with that of ampicillin and gentamicin. The effect is due to azido pharmacophore -CH2-CH(OH)-CH2-N3 (for N-(3-azido-2-hydroxypropyl)chitosan) or -CH2-CH2-N3 (for N-(2-azidoethyl)chitosan) introduced in chitosan chain, since the corresponding organic azides NH2-CH2-CH2-N3 and NH2-CH2-CH2-N3 are characterized by high antibacterial activity. However, high antibacterial organic azides NH2-CH2-CH2-N3 and NH2-CH2-CH2-N3 are characterized by high toxicity. Their conjugation to the chitosan chain saves their antibacterial effect, but strongly diminishes their toxicity, and the toxicity of the resulting derivatives is comparable with that of the starting chitosan. These findings are of interest to food science, since novel effective food coatings can be developed on basis of prepared derivatives.

By date By citations

Citations by journals

	2 4 6 8 10
International Journal of Biological Macromolecules	International Journal of Biological Macromolecules, 10, 19.61% International Journal of Biological Macromolecules 10 publications, 19.61%
Carbohydrate Polymers	Carbohydrate Polymers, 5, 9.8% Carbohydrate Polymers 5 publications, 9.8%
Food Chemistry	Food Chemistry, 3, 5.88% Food Chemistry 3 publications, 5.88%
Progress in Organic Coatings	Progress in Organic Coatings, 3, 5.88% Progress in Organic Coatings 3 publications, 5.88%
International Journal of Molecular Sciences	International Journal of Molecular Sciences, 2, 3.92% International Journal of Molecular Sciences 2 publications, 3.92%
Molecules	Molecules, 2, 3.92% Molecules 2 publications, 3.92%
Industrial Crops and Products	Industrial Crops and Products, 2, 3.92% Industrial Crops and Products 2 publications, 3.92%
Membranes	Membranes, 1, 1.96% Membranes 1 publication, 1.96%
Coatings	Coatings, 1, 1.96% Coatings 1 publication, 1.96%
Applied Sciences (Switzerland)	Applied Sciences (Switzerland), 1, 1.96% Applied Sciences (Switzerland) 1 publication, 1.96%
Frontiers in Bioengineering and Biotechnology	Frontiers in Bioengineering and Biotechnology, 1, 1.96% Frontiers in Bioengineering and Biotechnology 1 publication, 1.96%
Pharmaceutical Chemistry Journal	Pharmaceutical Chemistry Journal, 1, 1.96% Pharmaceutical Chemistry Journal 1 publication, 1.96%
Chinese Journal of Polymer Science (English Edition)	Chinese Journal of Polymer Science (English Edition), 1, 1.96% Chinese Journal of Polymer Science (English Edition) 1 publication, 1.96%
Environmental Research	Environmental Research, 1, 1.96% Environmental Research 1 publication, 1.96%
International Immunopharmacology	International Immunopharmacology, 1, 1.96% International Immunopharmacology 1 publication, 1.96%
Journal of Drug Delivery Science and Technology	Journal of Drug Delivery Science and Technology, 1, 1.96% Journal of Drug Delivery Science and Technology 1 publication, 1.96%
Materials Science and Engineering C	Materials Science and Engineering C, 1, 1.96% Materials Science and Engineering C 1 publication, 1.96%
Journal of Food Safety	Journal of Food Safety, 1, 1.96% Journal of Food Safety 1 publication, 1.96%
Starch/Staerke	Starch/Staerke, 1, 1.96% Starch/Staerke 1 publication, 1.96%
Journal of Food Processing and Preservation	Journal of Food Processing and Preservation, 1, 1.96% Journal of Food Processing and Preservation 1 publication, 1.96%
Advanced NanoBiomed Research	Advanced NanoBiomed Research, 1, 1.96% Advanced NanoBiomed Research 1 publication, 1.96%
Advanced Industrial and Engineering Polymer Research	Advanced Industrial and Engineering Polymer Research, 1, 1.96% Advanced Industrial and Engineering Polymer Research 1 publication, 1.96%
New Journal of Chemistry	New Journal of Chemistry, 1, 1.96% New Journal of Chemistry 1 publication, 1.96%
Polymers	Polymers, 1, 1.96% Polymers 1 publication, 1.96%
European Polymer Journal	European Polymer Journal, 1, 1.96% European Polymer Journal 1 publication, 1.96%
Biomass Conversion and Biorefinery	Biomass Conversion and Biorefinery, 1, 1.96% Biomass Conversion and Biorefinery 1 publication, 1.96%
Composites - Part A: Applied Science and Manufacturing	Composites - Part A: Applied Science and Manufacturing, 1, 1.96% Composites - Part A: Applied Science and Manufacturing 1 publication, 1.96%
Chemistry	Chemistry, 1, 1.96% Chemistry 1 publication, 1.96%

	2 4 6 8 10

Citations by publishers

	5 10 15 20 25 30
Elsevier	Elsevier, 30, 58.82% Elsevier 30 publications, 58.82%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 9, 17.65% Multidisciplinary Digital Publishing Institute (MDPI) 9 publications, 17.65%
Wiley	Wiley, 4, 7.84% Wiley 4 publications, 7.84%
Springer Nature	Springer Nature, 3, 5.88% Springer Nature 3 publications, 5.88%
Frontiers Media S.A.	Frontiers Media S.A., 1, 1.96% Frontiers Media S.A. 1 publication, 1.96%
Royal Society of Chemistry (RSC)	Royal Society of Chemistry (RSC), 1, 1.96% Royal Society of Chemistry (RSC) 1 publication, 1.96%
	5 10 15 20 25 30

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Kritchenkov A. S. et al. Novel non-toxic high efficient antibacterial azido chitosan derivatives with potential application in food coatings // Food Chemistry. 2019. Vol. 301. p. 125247.

GOST all authors (up to 50) Copy

Kritchenkov A. S., Egorov A. R., Kurasova M. N., Volkova O. V., Meledina T. V., Lipkan N. A., Tskhovrebov A., Kurliuk A. V., Shakola T. V., Dysin A. P., Egorov M. Yu., Savicheva E. A., Dos Santos W. M. Novel non-toxic high efficient antibacterial azido chitosan derivatives with potential application in food coatings // Food Chemistry. 2019. Vol. 301. p. 125247.

RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/j.foodchem.2019.125247

UR - https://doi.org/10.1016%2Fj.foodchem.2019.125247

TI - Novel non-toxic high efficient antibacterial azido chitosan derivatives with potential application in food coatings

T2 - Food Chemistry

AU - Kritchenkov, Andreii S.

AU - Egorov, Anton R

AU - Kurasova, Margarita N

AU - Volkova, Olga V

AU - Meledina, Tatyana V

AU - Lipkan, Nikita A

AU - Tskhovrebov, Alexander

AU - Kurliuk, Aleh V

AU - Shakola, Tatsiana V

AU - Dysin, Artem P.

AU - Egorov, Mikhail Yu

AU - Savicheva, Elizaveta A

AU - Dos Santos, Wesley Moreira

PY - 2019

DA - 2019/12/01 00:00:00

PB - Elsevier

SP - 125247

VL - 301

SN - 0308-8146

SN - 1873-7072

ER -

BibTex

Cite this

BibTex Copy

@article{2019_Kritchenkov,

author = {Andreii S. Kritchenkov and Anton R Egorov and Margarita N Kurasova and Olga V Volkova and Tatyana V Meledina and Nikita A Lipkan and Alexander Tskhovrebov and Aleh V Kurliuk and Tatsiana V Shakola and Artem P. Dysin and Mikhail Yu Egorov and Elizaveta A Savicheva and Wesley Moreira Dos Santos},

title = {Novel non-toxic high efficient antibacterial azido chitosan derivatives with potential application in food coatings},

journal = {Food Chemistry},

year = {2019},

volume = {301},

publisher = {Elsevier},

month = {dec},

url = {https://doi.org/10.1016%2Fj.foodchem.2019.125247},

pages = {125247},

doi = {10.1016/j.foodchem.2019.125247}

}

Found error?

Publisher

Elsevier

Journal

Food Chemistry

Quartile SCImago

Quartile WOS

Impact factor

8.8

ISSN

03088146 (Print)
18737072 (Electronic)

Labs

Laboratory of Chemistry of Coordination Compounds

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