Open Access
Open access
volume 243 pages 1-13

Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products

Nahoko UCHIYAMA 1
Satoru Matsuda 1
Maiko KAWAMURA 1
Yoshihiko Shimokawa 1
Ruri KIKURA-HANAJIRI 1
K. Aritake 2
Yoshihiro Urade 2
Yukihiro Goda 1
2
 
Department of Molecular Behavioral Biology, Osaka Bioscience Institute, 6-2-4 Furuedai, Suita-City, Osaka 565-0874, Japan
Publication typeJournal Article
Publication date2014-10-01
scimago Q1
wos Q1
SJR0.748
CiteScore4.6
Impact factor2.5
ISSN03790738, 18726283
Pathology and Forensic Medicine
Law
Abstract
Our continuous survey of illegal products in Japan revealed the new distribution of 15 designer drugs. We identified four synthetic cannabinoids, i.e., NNEI (1), 5-fluoro-NNEI (2), 5-chloro-NNEI (3) and NNEI indazole analog (4), and seven cathinone derivatives, i.e., MPHP (5), α-PHPP (6), α-POP (7), 3,4-dimethoxy-α-PVP (8), 4-fluoro-α-PVP (9), α-ethylaminopentiophenone (10) and N-ethyl-4-methylpentedrone (11). We also determined LY-2183240 (12) and its 2'-isomer (13), which were reported to inhibit endocannabinoid uptake, a methylphenidate analog, 3,4-dichloromethylphenidate (14), and an MDA analog, 5-APDB (15). No chemical and pharmaceutical data for compounds 3, 4, 6 and 7 had been reported, making this the first report on these compounds.
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GOST Copy
UCHIYAMA N. et al. Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products // Forensic Science International. 2014. Vol. 243. pp. 1-13.
GOST all authors (up to 50) Copy
UCHIYAMA N., Matsuda S., KAWAMURA M., Shimokawa Y., KIKURA-HANAJIRI R., Aritake K., Urade Y., Goda Y. Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products // Forensic Science International. 2014. Vol. 243. pp. 1-13.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.forsciint.2014.03.013
UR - https://doi.org/10.1016/j.forsciint.2014.03.013
TI - Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products
T2 - Forensic Science International
AU - UCHIYAMA, Nahoko
AU - Matsuda, Satoru
AU - KAWAMURA, Maiko
AU - Shimokawa, Yoshihiko
AU - KIKURA-HANAJIRI, Ruri
AU - Aritake, K.
AU - Urade, Yoshihiro
AU - Goda, Yukihiro
PY - 2014
DA - 2014/10/01
PB - Elsevier
SP - 1-13
VL - 243
PMID - 24769262
SN - 0379-0738
SN - 1872-6283
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2014_UCHIYAMA,
author = {Nahoko UCHIYAMA and Satoru Matsuda and Maiko KAWAMURA and Yoshihiko Shimokawa and Ruri KIKURA-HANAJIRI and K. Aritake and Yoshihiro Urade and Yukihiro Goda},
title = {Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products},
journal = {Forensic Science International},
year = {2014},
volume = {243},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/j.forsciint.2014.03.013},
pages = {1--13},
doi = {10.1016/j.forsciint.2014.03.013}
}