A highly selective fluorescent anthracene-based chemosensor for imaging Zn2+ in living cells and zebrafish
Minh Nguyen
1
,
Thi Hong Nguyen
1
,
Danh Quang Do
1
,
Hung D. Nguyen
1
,
Quan M Phung
2
,
Natesan Thirumalaivasan
3
,
Shu Z. Wu
3
,
1
Publication type: Journal Article
Publication date: 2020-05-01
scimago Q1
wos Q1
SJR: 0.758
CiteScore: 6.7
Impact factor: 5.4
ISSN: 13877003, 18790259
Materials Chemistry
Inorganic Chemistry
Physical and Theoretical Chemistry
Abstract
A new fluorescent chemosensor (An3) bearing anthracenyl rings was designed and developed for detection of Zn2+. Addition of Zn2+ into An3 gave rise to a fluorescent turn-on response at 424 nm whereas Al3+, Cd2+, Co2+, Cu2+, K+, Mg2+, Zn2+, Ca2+, Fe3+, Mn2+, Ni2+, Pb2+, and Hg2+ did not induce any emission intensity enhancement. Furthermore, the probe exhibited high selectivity toward Zn2+ and a very low detection limit (36 nM) based on chelation-enhanced fluorescence. Theoretical calculations revealed the possible formation of 1:1 and 1:2 complexes between An3 and Zn2+. In bioimaging experiments, the chemosensor displayed low cytotoxicity and good biocompatibility, rendering it an effective tool for fluorescent visualization of Zn2+ in living cells and zebrafish models.
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15
Total citations:
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Citations from 2025:
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(26.67%)
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GOST
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Nguyen M. et al. A highly selective fluorescent anthracene-based chemosensor for imaging Zn2+ in living cells and zebrafish // Inorganic Chemistry Communication. 2020. Vol. 115. p. 107882.
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Nguyen M., Nguyen T. H., Do D. Q., Nguyen H. D., Phung Q. M., Thirumalaivasan N., Wu S. Z., Dinh T. H. N. A highly selective fluorescent anthracene-based chemosensor for imaging Zn2+ in living cells and zebrafish // Inorganic Chemistry Communication. 2020. Vol. 115. p. 107882.
Cite this
RIS
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TY - JOUR
DO - 10.1016/j.inoche.2020.107882
UR - https://doi.org/10.1016/j.inoche.2020.107882
TI - A highly selective fluorescent anthracene-based chemosensor for imaging Zn2+ in living cells and zebrafish
T2 - Inorganic Chemistry Communication
AU - Nguyen, Minh
AU - Nguyen, Thi Hong
AU - Do, Danh Quang
AU - Nguyen, Hung D.
AU - Phung, Quan M
AU - Thirumalaivasan, Natesan
AU - Wu, Shu Z.
AU - Dinh, Thi Hong Nhung
PY - 2020
DA - 2020/05/01
PB - Elsevier
SP - 107882
VL - 115
SN - 1387-7003
SN - 1879-0259
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2020_Nguyen,
author = {Minh Nguyen and Thi Hong Nguyen and Danh Quang Do and Hung D. Nguyen and Quan M Phung and Natesan Thirumalaivasan and Shu Z. Wu and Thi Hong Nhung Dinh},
title = {A highly selective fluorescent anthracene-based chemosensor for imaging Zn2+ in living cells and zebrafish},
journal = {Inorganic Chemistry Communication},
year = {2020},
volume = {115},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.inoche.2020.107882},
pages = {107882},
doi = {10.1016/j.inoche.2020.107882}
}