In silico exploration natural compounds for the discovery of novel dnmt3a inhibitors as potential therapeutic agents for acute myeloid leukaemia
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Biotechnology Industry Research Assistance Council, Lodhi Road, New Delhi, India
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5
MIT Vishwaprayag University, Solapur - Pune Hwy, Kegaon, Solapur, 413255, India
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Publication type: Journal Article
Publication date: 2025-04-14
Abstract
BackgroundIn the current research, we focused on the critical role of DNA methylation in acute myeloid leukemia (AML) and the potential of DNMT3A inhibitors as therapeutic agents. The aberrant activity of DNMT3A is linked to poor patient outcomes, prompting the need for effective inhibitors.
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Das U. et al. In silico exploration natural compounds for the discovery of novel dnmt3a inhibitors as potential therapeutic agents for acute myeloid leukaemia // In Silico Research in Biomedicine. 2025. Vol. 1. p. 100006.
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Das U., Uttarkar A., Kumar J., Niranjan V. In silico exploration natural compounds for the discovery of novel dnmt3a inhibitors as potential therapeutic agents for acute myeloid leukaemia // In Silico Research in Biomedicine. 2025. Vol. 1. p. 100006.
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TY - JOUR
DO - 10.1016/j.insi.2025.100006
UR - https://linkinghub.elsevier.com/retrieve/pii/S3050787125000058
TI - In silico exploration natural compounds for the discovery of novel dnmt3a inhibitors as potential therapeutic agents for acute myeloid leukaemia
T2 - In Silico Research in Biomedicine
AU - Das, Uddalak
AU - Uttarkar, Akshay
AU - Kumar, Jitendra
AU - Niranjan, Vidya
PY - 2025
DA - 2025/04/14
PB - Elsevier
SP - 100006
VL - 1
SN - 3050-7871
ER -
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@article{2025_Das,
author = {Uddalak Das and Akshay Uttarkar and Jitendra Kumar and Vidya Niranjan},
title = {In silico exploration natural compounds for the discovery of novel dnmt3a inhibitors as potential therapeutic agents for acute myeloid leukaemia},
journal = {In Silico Research in Biomedicine},
year = {2025},
volume = {1},
publisher = {Elsevier},
month = {apr},
url = {https://linkinghub.elsevier.com/retrieve/pii/S3050787125000058},
pages = {100006},
doi = {10.1016/j.insi.2025.100006}
}
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