Blood cytokines in major depressive disorder in drug-naïve adolescents: A systematic review and meta-analysis
Kaustubh Kishor Jadhav
1, 2
,
Joud Daouk
1, 2
,
Karoliina Kurkinen
3
,
Siiri-Liisi Kraav
4
,
Päivi Eriksson
5
,
Per Eriksson
6
,
Tommi Tolmunen
7
,
Katja M. Kanninen
2
,
K. Kanninen
8
7
Publication type: Journal Article
Publication date: 2025-03-01
scimago Q1
wos Q1
SJR: 2.121
CiteScore: 9.5
Impact factor: 4.9
ISSN: 01650327, 15732517
PubMed ID:
39603515
Abstract
BackgroundMajor depressive disorder (MDD) is the most common mental health problem worldwide. Increased levels of inflammation are associated with MDD, though this relationship has been suggested to be bidirectional. The first incidence of a depressive episode usually occurs during adolescence. Hence, examining depressed, drug-naïve adolescents is important to understand the role of inflammation in the pathophysiology of MDD. Cytokines might play a crucial role in inflammation associated with MDD. Therefore, this article aims to investigate the changes in the levels of peripheral blood cytokines in adolescents with MDD.
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Metrics
13
Total citations:
13
Citations from 2024:
12
(92.31%)
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GOST
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Jadhav K. K. et al. Blood cytokines in major depressive disorder in drug-naïve adolescents: A systematic review and meta-analysis // Journal of Affective Disorders. 2025. Vol. 372. pp. 48-55.
GOST all authors (up to 50)
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Jadhav K. K., Daouk J., Kurkinen K., Kraav S., Eriksson P., Eriksson P., Tolmunen T., Kanninen K. M., Kanninen K. Blood cytokines in major depressive disorder in drug-naïve adolescents: A systematic review and meta-analysis // Journal of Affective Disorders. 2025. Vol. 372. pp. 48-55.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.jad.2024.11.071
UR - https://linkinghub.elsevier.com/retrieve/pii/S0165032724019621
TI - Blood cytokines in major depressive disorder in drug-naïve adolescents: A systematic review and meta-analysis
T2 - Journal of Affective Disorders
AU - Jadhav, Kaustubh Kishor
AU - Daouk, Joud
AU - Kurkinen, Karoliina
AU - Kraav, Siiri-Liisi
AU - Eriksson, Päivi
AU - Eriksson, Per
AU - Tolmunen, Tommi
AU - Kanninen, Katja M.
AU - Kanninen, K.
PY - 2025
DA - 2025/03/01
PB - Elsevier
SP - 48-55
VL - 372
PMID - 39603515
SN - 0165-0327
SN - 1573-2517
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2025_Jadhav,
author = {Kaustubh Kishor Jadhav and Joud Daouk and Karoliina Kurkinen and Siiri-Liisi Kraav and Päivi Eriksson and Per Eriksson and Tommi Tolmunen and Katja M. Kanninen and K. Kanninen},
title = {Blood cytokines in major depressive disorder in drug-naïve adolescents: A systematic review and meta-analysis},
journal = {Journal of Affective Disorders},
year = {2025},
volume = {372},
publisher = {Elsevier},
month = {mar},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0165032724019621},
pages = {48--55},
doi = {10.1016/j.jad.2024.11.071}
}