Executive Functioning Complaints and Escitalopram Treatment Response in Late-Life Depression
Publication type: Journal Article
Publication date: 2015-05-01
scimago Q1
wos Q1
SJR: 1.378
CiteScore: 8.5
Impact factor: 3.8
ISSN: 10647481, 15457214
PubMed ID:
24388222
Psychiatry and Mental health
Geriatrics and Gerontology
Abstract
Executive dysfunction may play a key role in the pathophysiology of late-life depression. Executive dysfunction can be assessed with cognitive tests and subjective report of difficulties with executive skills. The present study investigated the association between subjective report of executive functioning complaints and time to escitalopram treatment response in older adults with major depressive disorder (MDD).100 older adults with MDD (58 with executive functioning complaints and 42 without executive functioning complaints) completed a 12-week trial of escitalopram. Treatment response over 12 weeks, as measured by repeated Hamilton Depression Rating Scale scores, was compared for adults with and without executive complaints using mixed-effects modeling.Mixed effects analysis revealed a significant group × time interaction, F(1, 523.34) = 6.00, p = 0.01. Depressed older adults who reported executive functioning complaints at baseline demonstrated a slower response to escitalopram treatment than those without executive functioning complaints.Self-report of executive functioning difficulties may be a useful prognostic indicator for subsequent speed of response to antidepressant medication.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
|
|
|
American Journal of Geriatric Psychiatry
4 publications, 9.76%
|
|
|
Journal of Affective Disorders
3 publications, 7.32%
|
|
|
FOCUS The Journal of Lifelong Learning in Psychiatry
2 publications, 4.88%
|
|
|
Biomedicines
2 publications, 4.88%
|
|
|
Frontiers in Psychiatry
2 publications, 4.88%
|
|
|
Translational Psychiatry
2 publications, 4.88%
|
|
|
Depression and Anxiety
2 publications, 4.88%
|
|
|
Journal of the American Geriatrics Society
2 publications, 4.88%
|
|
|
Journal of Geriatric Psychiatry and Neurology
1 publication, 2.44%
|
|
|
Psychiatric Annals
1 publication, 2.44%
|
|
|
Neuropsychology Review
1 publication, 2.44%
|
|
|
Molecular Psychiatry
1 publication, 2.44%
|
|
|
Current Psychiatry Reports
1 publication, 2.44%
|
|
|
NeuroImage: Clinical
1 publication, 2.44%
|
|
|
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
1 publication, 2.44%
|
|
|
Seminars in Cell and Developmental Biology
1 publication, 2.44%
|
|
|
International Journal of Geriatric Psychiatry
1 publication, 2.44%
|
|
|
Aging and Mental Health
1 publication, 2.44%
|
|
|
Applied neuropsychology. Adult
1 publication, 2.44%
|
|
|
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
1 publication, 2.44%
|
|
|
Archives of Clinical Neuropsychology
1 publication, 2.44%
|
|
|
Annual Review of Clinical Psychology
1 publication, 2.44%
|
|
|
Annual Review of Medicine
1 publication, 2.44%
|
|
|
Orvosi Hetilap
1 publication, 2.44%
|
|
|
Journal of Behavior Therapy and Experimental Psychiatry
1 publication, 2.44%
|
|
|
Transcranial Magnetic Stimulation
1 publication, 2.44%
|
|
|
Journal of Alzheimer's Disease
1 publication, 2.44%
|
|
|
The American Journal of Geriatric Psychiatry Open Science Education and Practice
1 publication, 2.44%
|
|
|
1
2
3
4
|
Publishers
|
2
4
6
8
10
12
14
|
|
|
Elsevier
14 publications, 34.15%
|
|
|
Springer Nature
5 publications, 12.2%
|
|
|
Wiley
5 publications, 12.2%
|
|
|
American Psychiatric Association Publishing
2 publications, 4.88%
|
|
|
SAGE
2 publications, 4.88%
|
|
|
MDPI
2 publications, 4.88%
|
|
|
Frontiers Media S.A.
2 publications, 4.88%
|
|
|
Taylor & Francis
2 publications, 4.88%
|
|
|
Oxford University Press
2 publications, 4.88%
|
|
|
Annual Reviews
2 publications, 4.88%
|
|
|
SLACK
1 publication, 2.44%
|
|
|
Cambridge University Press
1 publication, 2.44%
|
|
|
Akademiai Kiado
1 publication, 2.44%
|
|
|
2
4
6
8
10
12
14
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
41
Total citations:
41
Citations from 2024:
4
(9.76%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Manning K. J. et al. Executive Functioning Complaints and Escitalopram Treatment Response in Late-Life Depression // American Journal of Geriatric Psychiatry. 2015. Vol. 23. No. 5. pp. 440-445.
GOST all authors (up to 50)
Copy
Manning K. J., ALEXOPOULOS G. S., Banerjee S., Morimoto S. S., Seirup J. K., Klimstra S. A., Yuen G., Kanellopoulos T., Gunning-Dixon F. Executive Functioning Complaints and Escitalopram Treatment Response in Late-Life Depression // American Journal of Geriatric Psychiatry. 2015. Vol. 23. No. 5. pp. 440-445.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.jagp.2013.11.005
UR - https://doi.org/10.1016/j.jagp.2013.11.005
TI - Executive Functioning Complaints and Escitalopram Treatment Response in Late-Life Depression
T2 - American Journal of Geriatric Psychiatry
AU - Manning, Kevin J
AU - ALEXOPOULOS, GEORGE S.
AU - Banerjee, Samprit
AU - Morimoto, Sarah Shizuko
AU - Seirup, Joanna K.
AU - Klimstra, Sibel A
AU - Yuen, Genevieve
AU - Kanellopoulos, Theodora
AU - Gunning-Dixon, Faith
PY - 2015
DA - 2015/05/01
PB - Elsevier
SP - 440-445
IS - 5
VL - 23
PMID - 24388222
SN - 1064-7481
SN - 1545-7214
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2015_Manning,
author = {Kevin J Manning and GEORGE S. ALEXOPOULOS and Samprit Banerjee and Sarah Shizuko Morimoto and Joanna K. Seirup and Sibel A Klimstra and Genevieve Yuen and Theodora Kanellopoulos and Faith Gunning-Dixon},
title = {Executive Functioning Complaints and Escitalopram Treatment Response in Late-Life Depression},
journal = {American Journal of Geriatric Psychiatry},
year = {2015},
volume = {23},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.jagp.2013.11.005},
number = {5},
pages = {440--445},
doi = {10.1016/j.jagp.2013.11.005}
}
Cite this
MLA
Copy
Manning, Kevin J., et al. “Executive Functioning Complaints and Escitalopram Treatment Response in Late-Life Depression.” American Journal of Geriatric Psychiatry, vol. 23, no. 5, May. 2015, pp. 440-445. https://doi.org/10.1016/j.jagp.2013.11.005.