Journal of Catalysis

, volume 418 , pages 283-289

Iridium-catalyzed reductive amination of carboxylic acids

Lin Ouyang ¹

Rui Miao ¹

Zhanhui Yang ²

Renshi Luo ^{1, 3}

Hide authors affiliations Show authors affiliations: 3 affiliations

School of Pharmaceutical Sciences, Gannan Medical University, Ganzhou 341000, Jiangxi Province, PR China |

Department of Organic Chemistry, College of chemistry, Beijing University of Chemical Technology, Beijing 100029, PR China |

College of Chemistry and Environmental Engineering, Shaoguan University, Shaoguan 512005, PR China |

Publication type: Journal Article

Publication date: 2023-02-01

Elsevier

Journal of Catalysis

scimago Q1

wos Q1

SJR: 1.558

CiteScore: 10.9

Impact factor: 6.5

ISSN: 00219517, 10902694

DOI: 10.1016/j.jcat.2023.01.030

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Catalysis

Physical and Theoretical Chemistry

Abstract

Our Ir-catalyzed reductive amination of carboxylic acids with amines produces structurally diverse N-alkylated amines in good to excellent yields (up to 60 examples). This protocol is advantageous of mild conditions, convenient operations, and excellent functionality tolerance. The synthetic values are highlighted through the synthesis of two pharmaceutical molecules-Cinacalcet and (R)-Fendiline.

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GOST |

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GOST Copy

Ouyang L. et al. Iridium-catalyzed reductive amination of carboxylic acids // Journal of Catalysis. 2023. Vol. 418. pp. 283-289.

GOST all authors (up to 50) Copy

Ouyang L., Miao R., Yang Z., Luo R. Iridium-catalyzed reductive amination of carboxylic acids // Journal of Catalysis. 2023. Vol. 418. pp. 283-289.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/j.jcat.2023.01.030

UR - https://doi.org/10.1016/j.jcat.2023.01.030

TI - Iridium-catalyzed reductive amination of carboxylic acids

T2 - Journal of Catalysis

AU - Ouyang, Lin

AU - Miao, Rui

AU - Yang, Zhanhui

AU - Luo, Renshi

PY - 2023

DA - 2023/02/01

PB - Elsevier

SP - 283-289

VL - 418

SN - 0021-9517

SN - 1090-2694

ER -

BibTex

Cite this

BibTex (up to 50 authors) Copy

@article{2023_Ouyang,

author = {Lin Ouyang and Rui Miao and Zhanhui Yang and Renshi Luo},

title = {Iridium-catalyzed reductive amination of carboxylic acids},

journal = {Journal of Catalysis},

year = {2023},

volume = {418},

publisher = {Elsevier},

month = {feb},

url = {https://doi.org/10.1016/j.jcat.2023.01.030},

pages = {283--289},

doi = {10.1016/j.jcat.2023.01.030}

}

Publisher

Elsevier

Journal

Journal of Catalysis

scimago Q1

wos Q1

SJR

1.558

CiteScore

10.9

Impact factor

6.5

ISSN

00219517 (Print)

10902694 (Electronic)

Profiles

Renshi Luo