Elsevier
Journal of Ethnopharmacology
,  volume 352 ,  pages 120184

Xiaoyaosan alleviates chronic psychological stress-induced TH17/Treg imbalance via modulation of the FKBP5/NF-κB axis

Zhang Yi 1
, 
Xiao-Ru Luo 2
, 
Yu-Hang Zhou 3, 4
, 
Qian-Yin Xue 5
, 
Shu-Ya Wu 5
, 
Jing-Yu Xu 5
, 
GUO-HUI LI 5
, 
Bu-Ping Liu 5
, 
Ming-Jia Zhang 6
, 
Guang-Dong Tong 1, 3
, 
Hai-Qing Ao 5
, 
Mian-Mian Liao 1
1
 
2
 
3
 
4
 
5
 
6
 
Publication type: Journal Article
Publication date: 2025-08-01
Elsevier
scimago Q1
wos Q1
SJR: 1.142
CiteScore: 10.4
Impact factor: 5.4
ISSN: 03788741, 18727573
Abstract
Ethnopharmacological relevanceXiaoyaosan (XYS), a classical herbal formulation indicated for “depression syndrome”, can improve chronic stress-related mood disorders and immune disorders through multi-target modulation of inflammatory mediators, although its precise mechanism in regulating Th17/Treg balance remains to be clarified.
Found 
Found 

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Zhang Yi et al. Xiaoyaosan alleviates chronic psychological stress-induced TH17/Treg imbalance via modulation of the FKBP5/NF-κB axis // Journal of Ethnopharmacology. 2025. Vol. 352. p. 120184.
GOST all authors (up to 50) Copy
Zhang Yi, Xiao-Ru Luo, Zhou Y., Xue Q., Wu S., Xu J., LI G., Liu B., Zhang M., Tong G., Ao H., Liao M. Xiaoyaosan alleviates chronic psychological stress-induced TH17/Treg imbalance via modulation of the FKBP5/NF-κB axis // Journal of Ethnopharmacology. 2025. Vol. 352. p. 120184.
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TY - JOUR
DO - 10.1016/j.jep.2025.120184
UR - https://linkinghub.elsevier.com/retrieve/pii/S0378874125008736
TI - Xiaoyaosan alleviates chronic psychological stress-induced TH17/Treg imbalance via modulation of the FKBP5/NF-κB axis
T2 - Journal of Ethnopharmacology
AU - Zhang Yi
AU - Xiao-Ru Luo
AU - Zhou, Yu-Hang
AU - Xue, Qian-Yin
AU - Wu, Shu-Ya
AU - Xu, Jing-Yu
AU - LI, GUO-HUI
AU - Liu, Bu-Ping
AU - Zhang, Ming-Jia
AU - Tong, Guang-Dong
AU - Ao, Hai-Qing
AU - Liao, Mian-Mian
PY - 2025
DA - 2025/08/01
PB - Elsevier
SP - 120184
VL - 352
SN - 0378-8741
SN - 1872-7573
ER -
BibTex
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@article{2025_Zhang Yi,
author = {Zhang Yi and Xiao-Ru Luo and Yu-Hang Zhou and Qian-Yin Xue and Shu-Ya Wu and Jing-Yu Xu and GUO-HUI LI and Bu-Ping Liu and Ming-Jia Zhang and Guang-Dong Tong and Hai-Qing Ao and Mian-Mian Liao},
title = {Xiaoyaosan alleviates chronic psychological stress-induced TH17/Treg imbalance via modulation of the FKBP5/NF-κB axis},
journal = {Journal of Ethnopharmacology},
year = {2025},
volume = {352},
publisher = {Elsevier},
month = {aug},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0378874125008736},
pages = {120184},
doi = {10.1016/j.jep.2025.120184}
}