Open Access
Open access
Elsevier
Journal of Microbiology, Immunology and Infection
,  volume 58 ,  issue 4 ,  pages 486-489

Unanticipated Cytotoxicity of Fusidic Acid in Antibiotic-loaded Hydrogel

Jing-Gu Jiang 1
, 
Yu-Chun Chen 2
, 
Ni-En Jiang 3
, 
Chun-Han Liao 4, 5
, 
Chih-Hung Chang 5, 6
1
 
Division of Hematology and Oncology, Department of Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan | 
2
 
3
 
Department of Orthopaedic Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan | 
4
 
Department of Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan | 
5
 
6
 
Publication type: Journal Article
Publication date: 2025-08-01
Elsevier
scimago Q1
wos Q2
SJR: 1.009
CiteScore: 10.1
Impact factor: 3.7
ISSN: 16841182, 19959133
Abstract
This study evaluated the cytotoxicity of fusidic acid-loaded HA hydrogels on different cell types. Results show significant cytotoxicity, especially at concentrations above 0.1 %, with MC3T3 cells being the most sensitive. These findings highlight the importance of considering cell-specific responses and cytotoxic effects when designing antibiotic-loaded hydrogels for biomedical applications.
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Jiang J. et al. Unanticipated Cytotoxicity of Fusidic Acid in Antibiotic-loaded Hydrogel // Journal of Microbiology, Immunology and Infection. 2025. Vol. 58. No. 4. pp. 486-489.
GOST all authors (up to 50) Copy
Jiang J., Chen Y., Jiang N., Liao C., Chang C. Unanticipated Cytotoxicity of Fusidic Acid in Antibiotic-loaded Hydrogel // Journal of Microbiology, Immunology and Infection. 2025. Vol. 58. No. 4. pp. 486-489.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.jmii.2025.02.004
UR - https://linkinghub.elsevier.com/retrieve/pii/S1684118225000374
TI - Unanticipated Cytotoxicity of Fusidic Acid in Antibiotic-loaded Hydrogel
T2 - Journal of Microbiology, Immunology and Infection
AU - Jiang, Jing-Gu
AU - Chen, Yu-Chun
AU - Jiang, Ni-En
AU - Liao, Chun-Han
AU - Chang, Chih-Hung
PY - 2025
DA - 2025/08/01
PB - Elsevier
SP - 486-489
IS - 4
VL - 58
SN - 1684-1182
SN - 1995-9133
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Jiang,
author = {Jing-Gu Jiang and Yu-Chun Chen and Ni-En Jiang and Chun-Han Liao and Chih-Hung Chang},
title = {Unanticipated Cytotoxicity of Fusidic Acid in Antibiotic-loaded Hydrogel},
journal = {Journal of Microbiology, Immunology and Infection},
year = {2025},
volume = {58},
publisher = {Elsevier},
month = {aug},
url = {https://linkinghub.elsevier.com/retrieve/pii/S1684118225000374},
number = {4},
pages = {486--489},
doi = {10.1016/j.jmii.2025.02.004}
}
MLA
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MLA Copy
Jiang, Jing-Gu, et al. “Unanticipated Cytotoxicity of Fusidic Acid in Antibiotic-loaded Hydrogel.” Journal of Microbiology, Immunology and Infection, vol. 58, no. 4, Aug. 2025, pp. 486-489. https://linkinghub.elsevier.com/retrieve/pii/S1684118225000374.