Pharmacological treatments for co-occurring PTSD and substance use disorders: A systematic review

Megan Swannell 1, 2
, 
Richard C J Bradlow 3
, 
Richard Charles John Bradlow 4
, 
Daniel Pham 4
, 
Jessica Gabriel 3, 4
, 
Yasmin Manahan 1, 2
, 
Shalini Arunogiri 5
1
 
Eastern Health Mental Health Service, Victoria, Australia. | 
2
 
Eastern Health Mental Health Service, Victoria, Australia | 
3
 
Turning Point, Eastern Health, Victoria, Australia | 
4
 
Turning Point, Eastern Health, Victoria, Australia. | 
5
 
Turning Point, Eastern Health, Victoria, Australia; Eastern Health Clinical School and Monash Addiction Research Centre, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia. Electronic address: Shalini.Arunogiri@monash.edu. | 
Publication type: Journal Article
Publication date: 2025-02-01
Elsevier
scimago Q1
wos Q3
SJR: 1.461
CiteScore: 6.6
Impact factor: 1.9
ISSN: 29498759, 29498767
Abstract
IntroductionPost-traumatic stress disorder and substance use disorders commonly co-occur and are associated with worse health outcomes. Currently, only psychosocial therapies are specifically recommended for use in the co-occurring population, but these come with numerous barriers to access and engagement. This study aims to identify potential pharmacological treatments to enhance treatment options and outcomes for this population.
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GOST Copy
Swannell M. et al. Pharmacological treatments for co-occurring PTSD and substance use disorders: A systematic review // Journal of Substance Use and Addiction Treatment. 2025. Vol. 169. p. 209601.
GOST all authors (up to 50) Copy
Swannell M., Bradlow R. C. J., Bradlow R. C. J., Pham D., Gabriel J., Manahan Y., Arunogiri S. Pharmacological treatments for co-occurring PTSD and substance use disorders: A systematic review // Journal of Substance Use and Addiction Treatment. 2025. Vol. 169. p. 209601.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.josat.2024.209601
UR - https://linkinghub.elsevier.com/retrieve/pii/S2949875924003138
TI - Pharmacological treatments for co-occurring PTSD and substance use disorders: A systematic review
T2 - Journal of Substance Use and Addiction Treatment
AU - Swannell, Megan
AU - Bradlow, Richard C J
AU - Bradlow, Richard Charles John
AU - Pham, Daniel
AU - Gabriel, Jessica
AU - Manahan, Yasmin
AU - Arunogiri, Shalini
PY - 2025
DA - 2025/02/01
PB - Elsevier
SP - 209601
VL - 169
PMID - 39672336
SN - 2949-8759
SN - 2949-8767
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Swannell,
author = {Megan Swannell and Richard C J Bradlow and Richard Charles John Bradlow and Daniel Pham and Jessica Gabriel and Yasmin Manahan and Shalini Arunogiri},
title = {Pharmacological treatments for co-occurring PTSD and substance use disorders: A systematic review},
journal = {Journal of Substance Use and Addiction Treatment},
year = {2025},
volume = {169},
publisher = {Elsevier},
month = {feb},
url = {https://linkinghub.elsevier.com/retrieve/pii/S2949875924003138},
pages = {209601},
doi = {10.1016/j.josat.2024.209601}
}