Resistin: A reappraisal
Publication type: Journal Article
Publication date: 2019-03-01
scimago Q1
wos Q1
SJR: 1.830
CiteScore: 11.4
Impact factor: 5.1
ISSN: 00476374, 18726216
PubMed ID:
30650338
Developmental Biology
Aging
Abstract
From a biological point of view, aging can be considered a progressive inability of an organism to react to stress, maintain homeostasis, and survive unfavourable changes during post-maturational life. The expression of several adipokines changes during aging and for some changes, a role in the onset of chronic disease and frailty has been proposed. Among adipokines, resistin was shown in recent studies to play a key role in aging. Resistin is a small secreted protein that regulates glucose metabolism in mammalians. High resistin levels induce insulin resistance and exert proinflammatory effects. Consistently, resistin has been shown to play a pivotal role in various metabolic, inflammatory, and autoimmune diseases. Herein, the role of resistin as a molecular link between aging and age-related conditions was reviewed and the clinical implications of this knowledge discussed.
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Metrics
154
Total citations:
154
Citations from 2024:
47
(30.52%)
Cite this
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RIS |
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GOST
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Acquarone E. et al. Resistin: A reappraisal // Mechanisms of Ageing and Development. 2019. Vol. 178. pp. 46-63.
GOST all authors (up to 50)
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Acquarone E., Monacelli F., Borghi R., Nencioni A., Odetti P. Resistin: A reappraisal // Mechanisms of Ageing and Development. 2019. Vol. 178. pp. 46-63.
Cite this
RIS
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TY - JOUR
DO - 10.1016/j.mad.2019.01.004
UR - https://doi.org/10.1016/j.mad.2019.01.004
TI - Resistin: A reappraisal
T2 - Mechanisms of Ageing and Development
AU - Acquarone, E
AU - Monacelli, Fiammetta
AU - Borghi, R.
AU - Nencioni, Alessio
AU - Odetti, P.
PY - 2019
DA - 2019/03/01
PB - Elsevier
SP - 46-63
VL - 178
PMID - 30650338
SN - 0047-6374
SN - 1872-6216
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2019_Acquarone,
author = {E Acquarone and Fiammetta Monacelli and R. Borghi and Alessio Nencioni and P. Odetti},
title = {Resistin: A reappraisal},
journal = {Mechanisms of Ageing and Development},
year = {2019},
volume = {178},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016/j.mad.2019.01.004},
pages = {46--63},
doi = {10.1016/j.mad.2019.01.004}
}