Mendeleev Communications, volume 33, issue 2, pages 191-193

Synthesis of 1-oxa-9-azaspiro[5.5]undecane-9-sulfonamides bearing a diverse molecular periphery and a rare zinc-binding group for carbonic anhydrase interrogation

Publication type: Journal Article
Publication date: 2023-03-01
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Impact factor: 1.9
ISSN: 09599436, 1364551X
General Chemistry
Abstract
A fundamentally novel type of molecular probes for the recognition by carbonic anhydrase zinc enzymes which constitute promising target family in diverse therapeutic areas has been designed and synthesized. To the best of our knowledge, these molecular tools of 1-oxa-9-azaspiro[5.5]-undecane-9-sulfonamide chemotype for the first time combine in their structure diversely substituted spirocyclic piperidines and an aminosulfamoyl moiety.
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Lukin A. Y. et al. Synthesis of 1-oxa-9-azaspiro[5.5]undecane-9-sulfonamides bearing a diverse molecular periphery and a rare zinc-binding group for carbonic anhydrase interrogation // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 191-193.
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Lukin A. Y., Vinogradova L., Komarova K., Kalinin S., Krasavin M. Synthesis of 1-oxa-9-azaspiro[5.5]undecane-9-sulfonamides bearing a diverse molecular periphery and a rare zinc-binding group for carbonic anhydrase interrogation // Mendeleev Communications. 2023. Vol. 33. No. 2. pp. 191-193.
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TY - JOUR
DO - 10.1016/j.mencom.2023.02.013
UR - https://doi.org/10.1016/j.mencom.2023.02.013
TI - Synthesis of 1-oxa-9-azaspiro[5.5]undecane-9-sulfonamides bearing a diverse molecular periphery and a rare zinc-binding group for carbonic anhydrase interrogation
T2 - Mendeleev Communications
AU - Lukin, Alexey Yu.
AU - Vinogradova, Lyubov
AU - Komarova, Kristina
AU - Kalinin, Stanislav
AU - Krasavin, Mikhail
PY - 2023
DA - 2023/03/01 00:00:00
PB - Elsevier
SP - 191-193
IS - 2
VL - 33
SN - 0959-9436
SN - 1364-551X
ER -
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@article{2023_Lukin,
author = {Alexey Yu. Lukin and Lyubov Vinogradova and Kristina Komarova and Stanislav Kalinin and Mikhail Krasavin},
title = {Synthesis of 1-oxa-9-azaspiro[5.5]undecane-9-sulfonamides bearing a diverse molecular periphery and a rare zinc-binding group for carbonic anhydrase interrogation},
journal = {Mendeleev Communications},
year = {2023},
volume = {33},
publisher = {Elsevier},
month = {mar},
url = {https://doi.org/10.1016/j.mencom.2023.02.013},
number = {2},
pages = {191--193},
doi = {10.1016/j.mencom.2023.02.013}
}
MLA
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Lukin, Alexey Yu., et al. “Synthesis of 1-oxa-9-azaspiro[5.5]undecane-9-sulfonamides bearing a diverse molecular periphery and a rare zinc-binding group for carbonic anhydrase interrogation.” Mendeleev Communications, vol. 33, no. 2, Mar. 2023, pp. 191-193. https://doi.org/10.1016/j.mencom.2023.02.013.
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