Comprehensive prediction of active components of raw and wine-processed Polygonati Rhizome based on chemical characterization, chemometrics, pharmacodynamics, and network pharmacology
Zhewen Zhang
1
,
Yutian Chen
2
,
Mingfang Zhao
2
,
Yue Lv
2
,
Yu Wang:
1
,
Liu Yang
1
,
Pei Ye
1
,
Yingjie Fang
1
,
Xianjie Kang
1
,
Xiaoning Li
1
,
Long Zhang
1, 3
,
Weihong Ge
1, 2, 3
,
Weifeng Du
1, 2, 3
1
2
Publication type: Journal Article
Publication date: 2025-06-01
scimago Q1
wos Q1
SJR: 0.750
CiteScore: 7.2
Impact factor: 5.1
ISSN: 0026265X, 10959149
Abstract
Ethnopharmacological relevanceA technique known as “processing” is used in traditional Chinese medicine to alter the composition of the components to reduce toxicity and enhance its effects. After processing, Polygonati Rhizoma (PR) can enhance the treatment of spleen-related disorders, although the active components remain unclear.
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Zhang Z. et al. Comprehensive prediction of active components of raw and wine-processed Polygonati Rhizome based on chemical characterization, chemometrics, pharmacodynamics, and network pharmacology // Microchemical Journal. 2025. Vol. 213. p. 113644.
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Zhang Z., Chen Y., Zhao M., Lv Y., Wang: Yu., Yang L., Ye P., Fang Y., Kang X., Li X., Zhang L., Ge W., Du W. Comprehensive prediction of active components of raw and wine-processed Polygonati Rhizome based on chemical characterization, chemometrics, pharmacodynamics, and network pharmacology // Microchemical Journal. 2025. Vol. 213. p. 113644.
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TY - JOUR
DO - 10.1016/j.microc.2025.113644
UR - https://linkinghub.elsevier.com/retrieve/pii/S0026265X25009981
TI - Comprehensive prediction of active components of raw and wine-processed Polygonati Rhizome based on chemical characterization, chemometrics, pharmacodynamics, and network pharmacology
T2 - Microchemical Journal
AU - Zhang, Zhewen
AU - Chen, Yutian
AU - Zhao, Mingfang
AU - Lv, Yue
AU - Wang:, Yu
AU - Yang, Liu
AU - Ye, Pei
AU - Fang, Yingjie
AU - Kang, Xianjie
AU - Li, Xiaoning
AU - Zhang, Long
AU - Ge, Weihong
AU - Du, Weifeng
PY - 2025
DA - 2025/06/01
PB - Elsevier
SP - 113644
VL - 213
SN - 0026-265X
SN - 1095-9149
ER -
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BibTex (up to 50 authors)
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@article{2025_Zhang,
author = {Zhewen Zhang and Yutian Chen and Mingfang Zhao and Yue Lv and Yu Wang: and Liu Yang and Pei Ye and Yingjie Fang and Xianjie Kang and Xiaoning Li and Long Zhang and Weihong Ge and Weifeng Du},
title = {Comprehensive prediction of active components of raw and wine-processed Polygonati Rhizome based on chemical characterization, chemometrics, pharmacodynamics, and network pharmacology},
journal = {Microchemical Journal},
year = {2025},
volume = {213},
publisher = {Elsevier},
month = {jun},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0026265X25009981},
pages = {113644},
doi = {10.1016/j.microc.2025.113644}
}
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