Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges
TADAO MAEDA
1, 2, 3
,
MICHIKO MANDAI
1, 2, 3
,
Sunao Sugita
1, 2, 3, 4
,
Cody Kime
2, 5
,
Masayo Takahashi
1, 2, 3, 4
1
Kobe City Eye Hospital, Department of Ophthalmology, Kobe 6500-047, Japan
|
3
Research Center, Kobe City Eye Hospital, Kobe 6500-047, Japan
|
4
Vision Care Inc., Kobe 650-0047, Japan
|
5
Trans Ova Genetics, Sioux Center, Iowa, USA
|
Publication type: Journal Article
Publication date: 2022-05-01
scimago Q1
wos Q1
SJR: 3.577
CiteScore: 21.9
Impact factor: 13.8
ISSN: 14714914, 1471499X
PubMed ID:
35370091
Molecular Biology
Molecular Medicine
Abstract
Stem cell-based therapy for retinal degeneration is transitioning from the research stage to the clinical stage and is being developed as a treatment across the globe. In clinical studies on induced pluripotent stem cell (iPSC)-derived retinal pigment epithelium (RPE) transplantation, the safety of the technique has started to clarify, and clinical study on further advances such as the long-desired transplantation of iPSC-derived retina to treat retinitis pigmentosa (RP) has begun. Ophthalmologists are now working closely with basic researchers to incorporate new technology areas with a synergy that is anticipated to realize the practical application of stem cell-based therapy for retinal degeneration.
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47
Total citations:
47
Citations from 2024:
27
(58.69%)
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GOST
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MAEDA T. et al. Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges // Trends in Molecular Medicine. 2022. Vol. 28. No. 5. pp. 388-404.
GOST all authors (up to 50)
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MAEDA T., MANDAI M., Sugita S., Kime C., Takahashi M. Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges // Trends in Molecular Medicine. 2022. Vol. 28. No. 5. pp. 388-404.
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RIS
Copy
TY - JOUR
DO - 10.1016/j.molmed.2022.03.001
UR - https://doi.org/10.1016/j.molmed.2022.03.001
TI - Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges
T2 - Trends in Molecular Medicine
AU - MAEDA, TADAO
AU - MANDAI, MICHIKO
AU - Sugita, Sunao
AU - Kime, Cody
AU - Takahashi, Masayo
PY - 2022
DA - 2022/05/01
PB - Elsevier
SP - 388-404
IS - 5
VL - 28
PMID - 35370091
SN - 1471-4914
SN - 1471-499X
ER -
Cite this
BibTex (up to 50 authors)
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@article{2022_MAEDA,
author = {TADAO MAEDA and MICHIKO MANDAI and Sunao Sugita and Cody Kime and Masayo Takahashi},
title = {Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges},
journal = {Trends in Molecular Medicine},
year = {2022},
volume = {28},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.molmed.2022.03.001},
number = {5},
pages = {388--404},
doi = {10.1016/j.molmed.2022.03.001}
}
Cite this
MLA
Copy
MAEDA, TADAO, et al. “Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges.” Trends in Molecular Medicine, vol. 28, no. 5, May. 2022, pp. 388-404. https://doi.org/10.1016/j.molmed.2022.03.001.