Mutation Research - Genetic Toxicology and Environmental Mutagenesis

, volume 564 , issue 1 , pages 83-88

Frequency of micronuclei in peripheral blood lymphocytes from subjects occupationally exposed to low levels of ionizing radiation

Lebana J. Joseph ¹

Uma N. Patwardhan ¹

ABAN M. SAMUEL ²

Hide authors affiliations Show authors affiliations: 2 affiliations

Isotope Group (BARC), Laboratory Nuclear Medicine Section, c/o Tata Memorial Centre Annexe, Parel, Mumbai 400012, India |

Thyrocare Metabolic Centre, Chembur, Mumbai 400071, India |

Publication type: Journal Article

Publication date: 2004-11-01

Elsevier

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

scimago Q2

wos Q2

SJR: 0.668

CiteScore: 4.4

Impact factor: 2.5

ISSN: 13835718, 18793592

DOI: 10.1016/j.mrgentox.2004.07.012

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PubMed ID: 15474414

Genetics

Health, Toxicology and Mutagenesis

Abstract

The aim of this study was to evaluate the genotoxic effect of low dose of occupational radiation exposure in Nuclear Medicine Department employees, by using cytokinesis-blocked micronucleus assay in peripheral blood lymphocytes. The study included 46 exposed individuals together with 27 from the same area without occupational exposure to radiation which served as controls. The results obtained were evaluated with respect to age, gender, smoking habits, pathological condition and the occupational exposure to radiation of the individuals. The frequency of micronuclei increased significantly with the age of the subjects (P = 0.007). However there were no significant differences in micronucleus frequency with gender, smoking habits and occupational exposure. The frequency of micronuclei was significantly higher in individuals with presence of pathological condition (P < 0.0001) in comparison to healthy population irrespective of their exposure status.

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Joseph L. J., Patwardhan U. N., SAMUEL A. M. Frequency of micronuclei in peripheral blood lymphocytes from subjects occupationally exposed to low levels of ionizing radiation // Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 2004. Vol. 564. No. 1. pp. 83-88.

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RIS |

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RIS Copy

TY - JOUR

DO - 10.1016/j.mrgentox.2004.07.012

UR - https://doi.org/10.1016/j.mrgentox.2004.07.012

TI - Frequency of micronuclei in peripheral blood lymphocytes from subjects occupationally exposed to low levels of ionizing radiation

T2 - Mutation Research - Genetic Toxicology and Environmental Mutagenesis

AU - Joseph, Lebana J.

AU - Patwardhan, Uma N.

AU - SAMUEL, ABAN M.

PY - 2004

DA - 2004/11/01

PB - Elsevier

SP - 83-88

IS - 1

VL - 564

PMID - 15474414

SN - 1383-5718

SN - 1879-3592

ER -

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BibTex (up to 50 authors) Copy

@article{2004_Joseph,

author = {Lebana J. Joseph and Uma N. Patwardhan and ABAN M. SAMUEL},

title = {Frequency of micronuclei in peripheral blood lymphocytes from subjects occupationally exposed to low levels of ionizing radiation},

journal = {Mutation Research - Genetic Toxicology and Environmental Mutagenesis},

year = {2004},

volume = {564},

publisher = {Elsevier},

month = {nov},

url = {https://doi.org/10.1016/j.mrgentox.2004.07.012},

number = {1},

pages = {83--88},

doi = {10.1016/j.mrgentox.2004.07.012}

}

MLA

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MLA Copy

Joseph, Lebana J., et al. “Frequency of micronuclei in peripheral blood lymphocytes from subjects occupationally exposed to low levels of ionizing radiation.” Mutation Research - Genetic Toxicology and Environmental Mutagenesis, vol. 564, no. 1, Nov. 2004, pp. 83-88. https://doi.org/10.1016/j.mrgentox.2004.07.012.

Publisher

Elsevier

Journal

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

scimago Q2

wos Q2

SJR

0.668

CiteScore

4.4

Impact factor

2.5

ISSN

13835718 (Print)

18793592 (Electronic)