volume 566 pages 97-111

Virtual reality modulating dynamics of neuroplasticity: Innovations in neuro-motor rehabilitation

Nitu L. Wankhede 1
Nitu Wankhede 2
SUSHRUTA KOPPULA 3
Suhas Ballal 4
Hardik Doshi 5, 6
Rohit Kumawat 7, 8, 9
SSrinadh Raju 10
S. Vamsee Raju 11
Isha Arora 12, 13
Shivkumar S. Sammeta 14
Shivkumar Sammeta 15
Ameeduzzafar Zafar 17, 18
Brijesh G. Taksande 2
Aman B. Upaganlawar 19, 20
Monica Gulati 21
Milind J. Umekar 2
Spandana Rajendra Kopalli 22
Mayur B. Kale 23
1
 
Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra 441002, India
2
 
Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra 441002, India.
5
 
Marwadi University Research Center, Department of Computer Engineering, Faculty of Engineering & Technology, Marwadi University, Rajkot 360003, Gujarat, India.
6
 
Marwadi University Research Center, Department of Computer Engineering, Faculty of Engineering & Technology, Marwadi University, Rajkot 360003, Gujarat, India
10
 
Department of Computer Science and Engineering, Raghu Engineering College, Vishakhapatnam 531162, Andhra Pradesh, India
11
 
Department of Computer Science and Engineering, Raghu Engineering College, Vishakhapatnam 531162, Andhra Pradesh, India.
12
 
Chandigarh Pharmacy College, Chandigarh Group of Colleges-Jhanjeri, Mohali, Punjab, India.
13
 
Chandigarh Pharmacy College, Chandigarh Group of Colleges-Jhanjeri, Mohali, Punjab, India
19
 
SNJB's Shriman Sureshdada Jain College of Pharmacy, Neminagar, Chandwad, Nashik, Maharashtra, India.
20
 
SNJB’s Shriman Sureshdada Jain College of Pharmacy, Neminagar, Chandwad, Nashik, Maharashtra, India
23
 
Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra 441002, India. Electronic address: mayur.kale28@gmail.com.
Publication typeJournal Article
Publication date2025-02-01
scimago Q2
wos Q3
SJR1.008
CiteScore5.6
Impact factor2.8
ISSN03064522, 18737544
Abstract
Virtual reality (VR) technology has emerged as a ground-breaking tool in neuroscience, revolutionizing our understanding of neuroplasticity and its implications for neurological rehabilitation. By immersing individuals in simulated environments, VR induces profound neurobiological transformations, affecting neuronal connectivity, sensory feedback mechanisms, motor learning processes, and cognitive functions. These changes highlight the dynamic interplay between molecular events, synaptic adaptations, and neural reorganization, emphasizing the potential of VR as a therapeutic intervention in various neurological disorders. This comprehensive review delves into the therapeutic applications of VR, focusing on its role in addressing multiple conditions such as stroke, traumatic brain injuries, phobias, and post-traumatic stress disorder. It highlights how VR can enhance motor recovery, cognitive rehabilitation, and emotional resilience, showcasing its potential as an innovative and effective tool in neurological rehabilitation. Integrating molecular neuroscience with VR technology allows for a deeper understanding of the molecular mechanisms underlying neuroplasticity, opening doors to personalized interventions and precise treatment strategies for individuals with neurological impairments. Moreover, the review emphasizes the ethical considerations and challenges that come with implementing VR-based interventions in clinical practice, stressing the importance of data privacy, informed consent, and collaborative interdisciplinary efforts. By leveraging advanced molecular imaging techniques, VR-based research methodologies, and computational modelling, the review envisions a future where VR technology plays a central role in revolutionizing neuroscience research and clinical neurorehabilitation, ultimately providing tailored and impactful solutions for individuals facing neurological challenges.
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GOST Copy
Wankhede N. L. et al. Virtual reality modulating dynamics of neuroplasticity: Innovations in neuro-motor rehabilitation // Neuroscience. 2025. Vol. 566. pp. 97-111.
GOST all authors (up to 50) Copy
Wankhede N. L., Wankhede N., KOPPULA S., Ballal S., Doshi H., Kumawat R., Raju S., Raju S. V., Arora I., Sammeta S. S., Sammeta S., Khalid M., Zafar A., Taksande B. G., Upaganlawar A. B., Gulati M., Umekar M. J., Kopalli S. R., Kale M. B. Virtual reality modulating dynamics of neuroplasticity: Innovations in neuro-motor rehabilitation // Neuroscience. 2025. Vol. 566. pp. 97-111.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.neuroscience.2024.12.040
UR - https://linkinghub.elsevier.com/retrieve/pii/S0306452224007474
TI - Virtual reality modulating dynamics of neuroplasticity: Innovations in neuro-motor rehabilitation
T2 - Neuroscience
AU - Wankhede, Nitu L.
AU - Wankhede, Nitu
AU - KOPPULA, SUSHRUTA
AU - Ballal, Suhas
AU - Doshi, Hardik
AU - Kumawat, Rohit
AU - Raju, SSrinadh
AU - Raju, S. Vamsee
AU - Arora, Isha
AU - Sammeta, Shivkumar S.
AU - Sammeta, Shivkumar
AU - Khalid, Mohammad
AU - Zafar, Ameeduzzafar
AU - Taksande, Brijesh G.
AU - Upaganlawar, Aman B.
AU - Gulati, Monica
AU - Umekar, Milind J.
AU - Kopalli, Spandana Rajendra
AU - Kale, Mayur B.
PY - 2025
DA - 2025/02/01
PB - Elsevier
SP - 97-111
VL - 566
PMID - 39722287
SN - 0306-4522
SN - 1873-7544
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Wankhede,
author = {Nitu L. Wankhede and Nitu Wankhede and SUSHRUTA KOPPULA and Suhas Ballal and Hardik Doshi and Rohit Kumawat and SSrinadh Raju and S. Vamsee Raju and Isha Arora and Shivkumar S. Sammeta and Shivkumar Sammeta and Mohammad Khalid and Ameeduzzafar Zafar and Brijesh G. Taksande and Aman B. Upaganlawar and Monica Gulati and Milind J. Umekar and Spandana Rajendra Kopalli and Mayur B. Kale},
title = {Virtual reality modulating dynamics of neuroplasticity: Innovations in neuro-motor rehabilitation},
journal = {Neuroscience},
year = {2025},
volume = {566},
publisher = {Elsevier},
month = {feb},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0306452224007474},
pages = {97--111},
doi = {10.1016/j.neuroscience.2024.12.040}
}
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