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Open access
Elsevier
Photodiagnosis and Photodynamic Therapy
,  volume 51 ,  pages 104457

Comparative analysis of combined methylene blue photodynamic therapy and doxorubicin treatment of oral squamous cell carcinoma cell line: in vitro study on apoptosis

Publication type: Journal Article
Publication date: 2025-02-01
Elsevier
scimago Q2
wos Q3
SJR: 0.724
CiteScore: 5.8
Impact factor: 2.6
ISSN: 15721000, 18731597
Abstract
IntroductionSquamous cell carcinoma (SCC) is the most common malignancy of the head and neck region. Combination therapy potentially enhances the effectiveness beyond that of each treatment alone. This study aimed to assess whether photodynamic therapy (PDT), using methylene blue as a photosensitizer in conjunction with doxorubicin, produces synergistic effects on the apoptosis of the oral squamous cell carcinoma (OSCC) cell line.
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Goujani S. M. et al. Comparative analysis of combined methylene blue photodynamic therapy and doxorubicin treatment of oral squamous cell carcinoma cell line: in vitro study on apoptosis // Photodiagnosis and Photodynamic Therapy. 2025. Vol. 51. p. 104457.
GOST all authors (up to 50) Copy
Goujani S. M., Koopaie M., Safarian F. H., Hakimiha N., Younespour S. Comparative analysis of combined methylene blue photodynamic therapy and doxorubicin treatment of oral squamous cell carcinoma cell line: in vitro study on apoptosis // Photodiagnosis and Photodynamic Therapy. 2025. Vol. 51. p. 104457.
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RIS Copy
TY - JOUR
DO - 10.1016/j.pdpdt.2024.104457
UR - https://linkinghub.elsevier.com/retrieve/pii/S1572100024004939
TI - Comparative analysis of combined methylene blue photodynamic therapy and doxorubicin treatment of oral squamous cell carcinoma cell line: in vitro study on apoptosis
T2 - Photodiagnosis and Photodynamic Therapy
AU - Goujani, Shayan Momeni
AU - Koopaie, Maryam
AU - Safarian, Fateme Hamta
AU - Hakimiha, Neda
AU - Younespour, Shima
PY - 2025
DA - 2025/02/01
PB - Elsevier
SP - 104457
VL - 51
PMID - 39732188
SN - 1572-1000
SN - 1873-1597
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Goujani,
author = {Shayan Momeni Goujani and Maryam Koopaie and Fateme Hamta Safarian and Neda Hakimiha and Shima Younespour},
title = {Comparative analysis of combined methylene blue photodynamic therapy and doxorubicin treatment of oral squamous cell carcinoma cell line: in vitro study on apoptosis},
journal = {Photodiagnosis and Photodynamic Therapy},
year = {2025},
volume = {51},
publisher = {Elsevier},
month = {feb},
url = {https://linkinghub.elsevier.com/retrieve/pii/S1572100024004939},
pages = {104457},
doi = {10.1016/j.pdpdt.2024.104457}
}
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