Mechanism exploration of Wenshen Jianpi Decoction on renoprotection in diabetic nephropathy via transcriptomics and metabolomics
Publication type: Journal Article
Publication date: 2025-04-01
scimago Q1
wos Q1
SJR: 1.694
CiteScore: 11.6
Impact factor: 8.3
ISSN: 09447113, 1618095X
Abstract
BackgroundDiabetic nephropathy (DN) is a severe chronic microvascular complications of diabetes mellitus and the leading cause of end-stage renal disease. Although many therapeutic approaches have been developed for treatment of DN, there is still a risk of disease progression. Wenshen Jianpi Decoction (WSJPD), a traditional Chinese medicine, have demonstrated considerable clinical efficacy in treating DN. However, the therapeutic mechanisms of WSJPD remain unclear.
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Deng Y. et al. Mechanism exploration of Wenshen Jianpi Decoction on renoprotection in diabetic nephropathy via transcriptomics and metabolomics // Phytomedicine. 2025. Vol. 139. p. 156446.
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Deng Y., ZHONG G., Jin T., Wang J., Peng X., Zhou K., Chen X., Cao X. Mechanism exploration of Wenshen Jianpi Decoction on renoprotection in diabetic nephropathy via transcriptomics and metabolomics // Phytomedicine. 2025. Vol. 139. p. 156446.
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TY - JOUR
DO - 10.1016/j.phymed.2025.156446
UR - https://linkinghub.elsevier.com/retrieve/pii/S094471132500087X
TI - Mechanism exploration of Wenshen Jianpi Decoction on renoprotection in diabetic nephropathy via transcriptomics and metabolomics
T2 - Phytomedicine
AU - Deng, Yingping
AU - ZHONG, GUANGHUI
AU - Jin, Tinglong
AU - Wang, Jin
AU - Peng, Xin
AU - Zhou, Kai
AU - Chen, Xiabo
AU - Cao, Xiaodan
PY - 2025
DA - 2025/04/01
PB - Elsevier
SP - 156446
VL - 139
SN - 0944-7113
SN - 1618-095X
ER -
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@article{2025_Deng,
author = {Yingping Deng and GUANGHUI ZHONG and Tinglong Jin and Jin Wang and Xin Peng and Kai Zhou and Xiabo Chen and Xiaodan Cao},
title = {Mechanism exploration of Wenshen Jianpi Decoction on renoprotection in diabetic nephropathy via transcriptomics and metabolomics},
journal = {Phytomedicine},
year = {2025},
volume = {139},
publisher = {Elsevier},
month = {apr},
url = {https://linkinghub.elsevier.com/retrieve/pii/S094471132500087X},
pages = {156446},
doi = {10.1016/j.phymed.2025.156446}
}