Schisandrin B ameliorates Alzheimer's disease by suppressing neuronal ferroptosis and ensuing microglia M1 polarization
Publication type: Journal Article
Publication date: 2025-07-01
scimago Q1
wos Q1
SJR: 1.694
CiteScore: 11.6
Impact factor: 8.3
ISSN: 09447113, 1618095X
Abstract
BackgroundAlzheimer's disease (AD) is a neurodegenerative disorder characterized by neuronal damage, with poor prognosis and limited therapeutic options. Inhibition of neuronal ferroptosis has shown promise as a potential treatment for AD. Schisandrin B (Sch B), a major active component of Schisandra chinensis, exhibits potential neuroprotective effects. However, whether Sch B inhibits neuronal ferroptosis remains unclear.
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Ding T. et al. Schisandrin B ameliorates Alzheimer's disease by suppressing neuronal ferroptosis and ensuing microglia M1 polarization // Phytomedicine. 2025. Vol. 142. p. 156780.
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Ding T., Song M., Wu Y., Li Zhu, Zhang S., Fan X. Schisandrin B ameliorates Alzheimer's disease by suppressing neuronal ferroptosis and ensuing microglia M1 polarization // Phytomedicine. 2025. Vol. 142. p. 156780.
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TY - JOUR
DO - 10.1016/j.phymed.2025.156780
UR - https://linkinghub.elsevier.com/retrieve/pii/S0944711325004180
TI - Schisandrin B ameliorates Alzheimer's disease by suppressing neuronal ferroptosis and ensuing microglia M1 polarization
T2 - Phytomedicine
AU - Ding, Tao
AU - Song, Meiying
AU - Wu, Yongshi
AU - Li Zhu
AU - Zhang, Shanshan
AU - Fan, Xiang
PY - 2025
DA - 2025/07/01
PB - Elsevier
SP - 156780
VL - 142
SN - 0944-7113
SN - 1618-095X
ER -
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@article{2025_Ding,
author = {Tao Ding and Meiying Song and Yongshi Wu and Li Zhu and Shanshan Zhang and Xiang Fan},
title = {Schisandrin B ameliorates Alzheimer's disease by suppressing neuronal ferroptosis and ensuing microglia M1 polarization},
journal = {Phytomedicine},
year = {2025},
volume = {142},
publisher = {Elsevier},
month = {jul},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0944711325004180},
pages = {156780},
doi = {10.1016/j.phymed.2025.156780}
}