Ent -kaurene diterpenoids and lignan from Leontopodium leontopodioides and their inhibitory activities against cyclooxygenases-1 and 2
Chu Lu Qi
1
,
En Wang
1
,
Li Qin Jin
1
,
Ming Yan
2
,
Xiaoqi Zhang Xiaoqi Zhang
3
,
Hao Wang
1
,
WENCAI YE
3
Publication type: Journal Article
Publication date: 2017-09-01
scimago Q3
wos Q3
SJR: 0.326
CiteScore: 2.9
Impact factor: 1.4
ISSN: 18743900, 18767486
Biochemistry
Plant Science
Biotechnology
Agronomy and Crop Science
Abstract
Two new ent-kaurene diterpenoids, 13α,15α-dihydroxy-18-carboxy-19-nor-ent-kaur-16-ene-2β-O-(2′-angelate)-β- d -glucopyranoside (leontocin A, 1), 13α,15α-dihydroxy-18-carboxy-19-nor-ent-kaur-16-ene-2β-O-(2′-angelate-6′-acetyl)-β- d -glucopyranoside (leontocin B, 2), and one new lignan, 2,3-bis[(3,4-di-hydroxyphenyl)methylene]-monoethyl ester-butanedioic acid (leontolignan A, 3), together with three known phenolic acids (4-6) were isolated from the aerial parts of Leontopodium leontopodioides (Asteraceae). Their structures were elucidated by chemical and spectroscopic methods. All isolates were evaluated for their anti-inflammatory activities by measuring their inhibitory effects against cyclooxygenase-1 and 2 in vitro.
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Total citations:
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Citations from 2024:
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(15.38%)
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Qi C. L. et al. Ent -kaurene diterpenoids and lignan from Leontopodium leontopodioides and their inhibitory activities against cyclooxygenases-1 and 2 // Phytochemistry Letters. 2017. Vol. 21. pp. 94-97.
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Qi C. L., Wang E., Jin L. Q., Yan M., Xiaoqi Zhang X. Z., Wang H., YE W. Ent -kaurene diterpenoids and lignan from Leontopodium leontopodioides and their inhibitory activities against cyclooxygenases-1 and 2 // Phytochemistry Letters. 2017. Vol. 21. pp. 94-97.
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TY - JOUR
DO - 10.1016/j.phytol.2017.06.019
UR - https://doi.org/10.1016/j.phytol.2017.06.019
TI - Ent -kaurene diterpenoids and lignan from Leontopodium leontopodioides and their inhibitory activities against cyclooxygenases-1 and 2
T2 - Phytochemistry Letters
AU - Qi, Chu Lu
AU - Wang, En
AU - Jin, Li Qin
AU - Yan, Ming
AU - Xiaoqi Zhang, Xiaoqi Zhang
AU - Wang, Hao
AU - YE, WENCAI
PY - 2017
DA - 2017/09/01
PB - Elsevier
SP - 94-97
VL - 21
SN - 1874-3900
SN - 1876-7486
ER -
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BibTex (up to 50 authors)
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@article{2017_Qi,
author = {Chu Lu Qi and En Wang and Li Qin Jin and Ming Yan and Xiaoqi Zhang Xiaoqi Zhang and Hao Wang and WENCAI YE},
title = {Ent -kaurene diterpenoids and lignan from Leontopodium leontopodioides and their inhibitory activities against cyclooxygenases-1 and 2},
journal = {Phytochemistry Letters},
year = {2017},
volume = {21},
publisher = {Elsevier},
month = {sep},
url = {https://doi.org/10.1016/j.phytol.2017.06.019},
pages = {94--97},
doi = {10.1016/j.phytol.2017.06.019}
}