Open Access
A novel, swift, and effective green synthesis of morpholino-pyridine analogues in microwave irradiation conditions
Publication type: Journal Article
Publication date: 2023-01-01
scimago Q2
wos Q2
SJR: 0.605
CiteScore: 4.8
Impact factor: 4.2
ISSN: 22117156
General Chemistry
Abstract
We report a facile, efficient, and environmentally benign approach for preparing morpholino-linked 1,4-dihydropyridine derivatives. The four-component fusion of morpholin-4-amine, diethyl acetylene dicarboxylate, malononitrile, and chosen substituted benzaldehydes occurred under microwave irradiation under mild conditions in the presence of potassium carbonate as a catalyst. This protocol offers remarkable benefits such as excellent yields (92–98 %), easy handling, simple workup, economy, cleaner reaction profile, green conditions, shorter reaction time (≤10 min), and avoiding column chromatography for purification.
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Metrics
12
Total citations:
12
Citations from 2024:
8
(66.67%)
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GOST
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Kumar K. S. et al. A novel, swift, and effective green synthesis of morpholino-pyridine analogues in microwave irradiation conditions // Results in Chemistry. 2023. Vol. 5. p. 100692.
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Kumar K. S., Robert A. R., Kerru N., Maddila S. A novel, swift, and effective green synthesis of morpholino-pyridine analogues in microwave irradiation conditions // Results in Chemistry. 2023. Vol. 5. p. 100692.
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RIS
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TY - JOUR
DO - 10.1016/j.rechem.2022.100692
UR - https://doi.org/10.1016/j.rechem.2022.100692
TI - A novel, swift, and effective green synthesis of morpholino-pyridine analogues in microwave irradiation conditions
T2 - Results in Chemistry
AU - Kumar, Komati Satish
AU - Robert, Alice Rinky
AU - Kerru, Nagaraju
AU - Maddila, Suresh
PY - 2023
DA - 2023/01/01
PB - Elsevier
SP - 100692
VL - 5
SN - 2211-7156
ER -
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BibTex (up to 50 authors)
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@article{2023_Kumar,
author = {Komati Satish Kumar and Alice Rinky Robert and Nagaraju Kerru and Suresh Maddila},
title = {A novel, swift, and effective green synthesis of morpholino-pyridine analogues in microwave irradiation conditions},
journal = {Results in Chemistry},
year = {2023},
volume = {5},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/j.rechem.2022.100692},
pages = {100692},
doi = {10.1016/j.rechem.2022.100692}
}