Biomarkers, Omics and Artificial Intelligence for Early Detection of Pancreatic Cancer.
Kate Murray
1
,
Lucy Oldfield
1
,
Irena Stefanova
1
,
Manuel Gentiluomo
2
,
Paolo Aretini
3
,
Rachel O'Sullivan
1
,
William Greenhalf
1
,
Salvatore Paiella
4
,
Mateus N. Aoki
5
,
Aldo Pastore
6
,
James Birch-Ford
1
,
Bhavana Hemantha Rao
7
,
Pinar Uysal-Onganer
8
,
Caoimhe M. Walsh
9
,
George B. Hanna
9
,
Jagriti Narang
10
,
Pradakshina Sharma
10
,
Daniele Campa
2
,
Cosmeri Rizzato
2
,
Andrei Turtoi
11
1
3
Fondazione Pisana per la Scienza ONLUS, Italy
|
8
School of Life Sciences, Cancer Mechanisms and Biomarkers Group, The University of Westminster, United Kingdom
|
Publication type: Journal Article
Publication date: 2025-06-01
scimago Q1
wos Q1
SJR: 4.016
CiteScore: 35.0
Impact factor: 15.7
ISSN: 1044579X, 10963650
Abstract
Pancreatic ductal adenocarcinoma (PDAC) is frequently diagnosed in its late stages when treatment options are limited. Unlike other common cancers, there are no population-wide screening programmes for PDAC. Thus, early disease detection, although urgently needed, remains elusive. Individuals in certain high-risk groups are, however, offered screening or surveillance. Here we explore advances in understanding high-risk groups for PDAC and efforts to implement biomarker-driven detection of PDAC in these groups. We review current approaches to early detection biomarker development and the use of artificial intelligence as applied to electronic health records (EHRs) and social media. Finally, we address the cost-effectiveness of applying biomarker strategies for early detection of PDAC.
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Metrics
15
Total citations:
15
Citations from 2024:
14
(93.33%)
Cite this
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RIS |
BibTex
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GOST
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Murray K. et al. Biomarkers, Omics and Artificial Intelligence for Early Detection of Pancreatic Cancer. // Seminars in Cancer Biology. 2025. Vol. 111. pp. 76-88.
GOST all authors (up to 50)
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Murray K., Oldfield L., Stefanova I., Gentiluomo M., Aretini P., O'Sullivan R., Greenhalf W., Paiella S., Aoki M. N., Pastore A., Birch-Ford J., Rao B. H., Uysal-Onganer P., Walsh C. M., Hanna G. B., Narang J., Sharma P., Campa D., Rizzato C., Turtoi A. Biomarkers, Omics and Artificial Intelligence for Early Detection of Pancreatic Cancer. // Seminars in Cancer Biology. 2025. Vol. 111. pp. 76-88.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.semcancer.2025.02.009
UR - https://linkinghub.elsevier.com/retrieve/pii/S1044579X25000379
TI - Biomarkers, Omics and Artificial Intelligence for Early Detection of Pancreatic Cancer.
T2 - Seminars in Cancer Biology
AU - Murray, Kate
AU - Oldfield, Lucy
AU - Stefanova, Irena
AU - Gentiluomo, Manuel
AU - Aretini, Paolo
AU - O'Sullivan, Rachel
AU - Greenhalf, William
AU - Paiella, Salvatore
AU - Aoki, Mateus N.
AU - Pastore, Aldo
AU - Birch-Ford, James
AU - Rao, Bhavana Hemantha
AU - Uysal-Onganer, Pinar
AU - Walsh, Caoimhe M.
AU - Hanna, George B.
AU - Narang, Jagriti
AU - Sharma, Pradakshina
AU - Campa, Daniele
AU - Rizzato, Cosmeri
AU - Turtoi, Andrei
PY - 2025
DA - 2025/06/01
PB - Elsevier
SP - 76-88
VL - 111
SN - 1044-579X
SN - 1096-3650
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2025_Murray,
author = {Kate Murray and Lucy Oldfield and Irena Stefanova and Manuel Gentiluomo and Paolo Aretini and Rachel O'Sullivan and William Greenhalf and Salvatore Paiella and Mateus N. Aoki and Aldo Pastore and James Birch-Ford and Bhavana Hemantha Rao and Pinar Uysal-Onganer and Caoimhe M. Walsh and George B. Hanna and Jagriti Narang and Pradakshina Sharma and Daniele Campa and Cosmeri Rizzato and Andrei Turtoi},
title = {Biomarkers, Omics and Artificial Intelligence for Early Detection of Pancreatic Cancer.},
journal = {Seminars in Cancer Biology},
year = {2025},
volume = {111},
publisher = {Elsevier},
month = {jun},
url = {https://linkinghub.elsevier.com/retrieve/pii/S1044579X25000379},
pages = {76--88},
doi = {10.1016/j.semcancer.2025.02.009}
}
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