Mesenchymal Stem Cells in Fibrotic Disease.
E. El Agha
1, 2
,
Rafael Kramann
3
,
Rebekka K. Schneider
4, 5
,
Xiaokun Li
2
,
WERNER SEEGER
1, 6
,
Benjamin D. Humphreys
7
,
Saverio Bellusci
1, 2
Publication type: Journal Article
Publication date: 2017-08-03
scimago Q1
wos Q1
SJR: 9.313
CiteScore: 32.9
Impact factor: 20.4
ISSN: 19345909, 18759777
PubMed ID:
28777943
Cell Biology
Genetics
Molecular Medicine
Abstract
Fibrosis is associated with organ failure and high mortality and is commonly characterized by aberrant myofibroblast accumulation. Investigating the cellular origin of myofibroblasts in various diseases is thus a promising strategy for developing targeted anti-fibrotic treatments. Recent studies using genetic lineage tracing technology have implicated diverse organ-resident perivascular mesenchymal stem cell (MSC)-like cells and bone marrow-MSCs in myofibroblast generation during fibrosis development. In this Review, we give an overview of the emerging role of MSCs and MSC-like cells in myofibroblast-mediated fibrotic disease in the kidney, lung, heart, liver, skin, and bone marrow.
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Metrics
363
Total citations:
363
Citations from 2024:
82
(22.59%)
Cite this
GOST |
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BibTex |
MLA
Cite this
GOST
Copy
El Agha E. et al. Mesenchymal Stem Cells in Fibrotic Disease. // Cell Stem Cell. 2017. Vol. 21. No. 2. pp. 166-177.
GOST all authors (up to 50)
Copy
El Agha E., Kramann R., Schneider R. K., Li X., SEEGER W., Humphreys B. D., Bellusci S. Mesenchymal Stem Cells in Fibrotic Disease. // Cell Stem Cell. 2017. Vol. 21. No. 2. pp. 166-177.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/j.stem.2017.07.011
UR - https://doi.org/10.1016/j.stem.2017.07.011
TI - Mesenchymal Stem Cells in Fibrotic Disease.
T2 - Cell Stem Cell
AU - El Agha, E.
AU - Kramann, Rafael
AU - Schneider, Rebekka K.
AU - Li, Xiaokun
AU - SEEGER, WERNER
AU - Humphreys, Benjamin D.
AU - Bellusci, Saverio
PY - 2017
DA - 2017/08/03
PB - Elsevier
SP - 166-177
IS - 2
VL - 21
PMID - 28777943
SN - 1934-5909
SN - 1875-9777
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2017_El Agha,
author = {E. El Agha and Rafael Kramann and Rebekka K. Schneider and Xiaokun Li and WERNER SEEGER and Benjamin D. Humphreys and Saverio Bellusci},
title = {Mesenchymal Stem Cells in Fibrotic Disease.},
journal = {Cell Stem Cell},
year = {2017},
volume = {21},
publisher = {Elsevier},
month = {aug},
url = {https://doi.org/10.1016/j.stem.2017.07.011},
number = {2},
pages = {166--177},
doi = {10.1016/j.stem.2017.07.011}
}
Cite this
MLA
Copy
El Agha, E., et al. “Mesenchymal Stem Cells in Fibrotic Disease..” Cell Stem Cell, vol. 21, no. 2, Aug. 2017, pp. 166-177. https://doi.org/10.1016/j.stem.2017.07.011.