Tetrahedron, volume 74, issue 1, pages 96-103

First synthetic approach towards K-259-2, a unique calmodulin antagonist

Shyam Basak ^{1, 2, 3}

Smita Mandal ^{1, 2, 3}

Dipakranjan Mal ^{1, 2, 3}

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DEPARTMENT OF CHEMISTRY

Indian Institute of Technology Kharagpur |

Kharagpur 721302 India, . |

Publication type: Journal Article

Publication date: 2018-01-01

Elsevier

Journal: Tetrahedron

scimago Q3

wos Q2

SJR: 0.406

CiteScore: 3.9

Impact factor: 2.1

ISSN: 00404020, 14645416

DOI: 10.1016/j.tet.2017.11.037

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Organic Chemistry

Drug Discovery

Biochemistry

Abstract

K-259-2, a unique calmodulin antagonist, is an allyl chain containing anthraquinone natural product. A regiospecific synthetic approach towards K-259-2 is herein represented. The study also showcases a protocol for synthesizing heavily substituted bromo naphthoate which was found to be suitable for fabricating the K-259-2 motif.

Found

	1
MolBank	MolBank, 1, 16.67% MolBank 1 publication, 16.67%
Chemistry of Heterocyclic Compounds	Chemistry of Heterocyclic Compounds, 1, 16.67% Chemistry of Heterocyclic Compounds 1 publication, 16.67%
Tetrahedron	Tetrahedron, 1, 16.67% Tetrahedron 1 publication, 16.67%
	1

	1
MDPI	MDPI, 1, 16.67% MDPI 1 publication, 16.67%
Springer Nature	Springer Nature, 1, 16.67% Springer Nature 1 publication, 16.67%
Elsevier	Elsevier, 1, 16.67% Elsevier 1 publication, 16.67%
Wiley	Wiley, 1, 16.67% Wiley 1 publication, 16.67%
	1

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Publisher

Elsevier

Journal

Tetrahedron

scimago Q3

wos Q2

SJR

0.406

CiteScore

3.9

Impact factor

2.1

ISSN

00404020 (Print)

14645416 (Electronic)

First synthetic approach towards K-259-2, a unique calmodulin antagonist

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