An efficient stereoselective synthesis of (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol from (S)-diethylmalate
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BioCryst Pharmaceuticals, Inc., 2190 Parkway Lake Drive, Birmingham, AL 35244, USA
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Publication type: Journal Article
Publication date: 2005-05-01
scimago Q3
wos Q3
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
A concise stereoselective synthesis of an imino sugar, (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol from (S)-diethylmalate has been developed in five steps and in overall yield of 28%.
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Kotian P. L., Chand P. An efficient stereoselective synthesis of (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol from (S)-diethylmalate // Tetrahedron Letters. 2005. Vol. 46. No. 19. pp. 3327-3330.
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Kotian P. L., Chand P. An efficient stereoselective synthesis of (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol from (S)-diethylmalate // Tetrahedron Letters. 2005. Vol. 46. No. 19. pp. 3327-3330.
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TY - JOUR
DO - 10.1016/j.tetlet.2005.03.077
UR - https://doi.org/10.1016/j.tetlet.2005.03.077
TI - An efficient stereoselective synthesis of (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol from (S)-diethylmalate
T2 - Tetrahedron Letters
AU - Kotian, Pravin L.
AU - Chand, Pooran
PY - 2005
DA - 2005/05/01
PB - Elsevier
SP - 3327-3330
IS - 19
VL - 46
SN - 0040-4039
SN - 1873-3581
ER -
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BibTex (up to 50 authors)
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@article{2005_Kotian,
author = {Pravin L. Kotian and Pooran Chand},
title = {An efficient stereoselective synthesis of (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol from (S)-diethylmalate},
journal = {Tetrahedron Letters},
year = {2005},
volume = {46},
publisher = {Elsevier},
month = {may},
url = {https://doi.org/10.1016/j.tetlet.2005.03.077},
number = {19},
pages = {3327--3330},
doi = {10.1016/j.tetlet.2005.03.077}
}
Cite this
MLA
Copy
Kotian, Pravin L., and Pooran Chand. “An efficient stereoselective synthesis of (3S,4R)-4-(hydroxymethyl)pyrrolidin-3-ol from (S)-diethylmalate.” Tetrahedron Letters, vol. 46, no. 19, May. 2005, pp. 3327-3330. https://doi.org/10.1016/j.tetlet.2005.03.077.