A synthetic study on gymnastatins F and Q: the tandem Michael and aldol reaction approach
Publication type: Journal Article
Publication date: 2009-07-01
scimago Q3
wos Q3
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
Gymnastatins F (1) and Q (2) were successfully synthesized using the tandem Michael and aldol reaction of the corresponding spirodienones with hemiacetal functions. Inspection of the optical purities of the substrates suggested that undesired racemization does not proceed during the tandem reaction. Results of theoretical calculations agreed with the ratio of the reaction outcome.
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Murayama K. et al. A synthetic study on gymnastatins F and Q: the tandem Michael and aldol reaction approach // Tetrahedron Letters. 2009. Vol. 50. No. 26. pp. 3191-3194.
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Murayama K., Tanabe T., Ishikawa Y., Nakamura K., Nishiyama S. A synthetic study on gymnastatins F and Q: the tandem Michael and aldol reaction approach // Tetrahedron Letters. 2009. Vol. 50. No. 26. pp. 3191-3194.
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RIS
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TY - JOUR
DO - 10.1016/j.tetlet.2009.01.156
UR - https://doi.org/10.1016/j.tetlet.2009.01.156
TI - A synthetic study on gymnastatins F and Q: the tandem Michael and aldol reaction approach
T2 - Tetrahedron Letters
AU - Murayama, Kyoko
AU - Tanabe, Takamasa
AU - Ishikawa, Yuichi
AU - Nakamura, Kensuke
AU - Nishiyama, Shigeru
PY - 2009
DA - 2009/07/01
PB - Elsevier
SP - 3191-3194
IS - 26
VL - 50
SN - 0040-4039
SN - 1873-3581
ER -
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BibTex (up to 50 authors)
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@article{2009_Murayama,
author = {Kyoko Murayama and Takamasa Tanabe and Yuichi Ishikawa and Kensuke Nakamura and Shigeru Nishiyama},
title = {A synthetic study on gymnastatins F and Q: the tandem Michael and aldol reaction approach},
journal = {Tetrahedron Letters},
year = {2009},
volume = {50},
publisher = {Elsevier},
month = {jul},
url = {https://doi.org/10.1016/j.tetlet.2009.01.156},
number = {26},
pages = {3191--3194},
doi = {10.1016/j.tetlet.2009.01.156}
}
Cite this
MLA
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Murayama, Kyoko, et al. “A synthetic study on gymnastatins F and Q: the tandem Michael and aldol reaction approach.” Tetrahedron Letters, vol. 50, no. 26, Jul. 2009, pp. 3191-3194. https://doi.org/10.1016/j.tetlet.2009.01.156.