Semisynthesis of miltirone, 1,2-dehydromiltirone, saligerone from carnosic acid and cytotoxities of their derivatives
Publication type: Journal Article
Publication date: 2018-06-01
scimago Q3
wos Q3
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
Miltirone, 1,2-dehydromiltirone, saligerone have been synthesized form carnosic acid. Among them, one step transformation of carnosic acid into miltirone was realized when decarboxylation/aromatization was promoted by Lewis acid. Moreover, 4 derivatives exhibited potent cytotoxic activities against three human cancer lines in vitro.
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Li C. J. et al. Semisynthesis of miltirone, 1,2-dehydromiltirone, saligerone from carnosic acid and cytotoxities of their derivatives // Tetrahedron Letters. 2018. Vol. 59. No. 26. pp. 2607-2609.
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Li C. J., Xia F., Zhang W., Wang K., Xu G., Qin H. Semisynthesis of miltirone, 1,2-dehydromiltirone, saligerone from carnosic acid and cytotoxities of their derivatives // Tetrahedron Letters. 2018. Vol. 59. No. 26. pp. 2607-2609.
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RIS
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TY - JOUR
DO - 10.1016/j.tetlet.2018.05.073
UR - https://doi.org/10.1016/j.tetlet.2018.05.073
TI - Semisynthesis of miltirone, 1,2-dehydromiltirone, saligerone from carnosic acid and cytotoxities of their derivatives
T2 - Tetrahedron Letters
AU - Li, Cheng Ji
AU - Xia, Fan
AU - Zhang, Wen
AU - Wang, Kou
AU - Xu, Gang
AU - Qin, Hong-Bo
PY - 2018
DA - 2018/06/01
PB - Elsevier
SP - 2607-2609
IS - 26
VL - 59
SN - 0040-4039
SN - 1873-3581
ER -
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BibTex (up to 50 authors)
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@article{2018_Li,
author = {Cheng Ji Li and Fan Xia and Wen Zhang and Kou Wang and Gang Xu and Hong-Bo Qin},
title = {Semisynthesis of miltirone, 1,2-dehydromiltirone, saligerone from carnosic acid and cytotoxities of their derivatives},
journal = {Tetrahedron Letters},
year = {2018},
volume = {59},
publisher = {Elsevier},
month = {jun},
url = {https://doi.org/10.1016/j.tetlet.2018.05.073},
number = {26},
pages = {2607--2609},
doi = {10.1016/j.tetlet.2018.05.073}
}
Cite this
MLA
Copy
Li, Cheng Ji, et al. “Semisynthesis of miltirone, 1,2-dehydromiltirone, saligerone from carnosic acid and cytotoxities of their derivatives.” Tetrahedron Letters, vol. 59, no. 26, Jun. 2018, pp. 2607-2609. https://doi.org/10.1016/j.tetlet.2018.05.073.