volume 41 issue 11 pages 974-983

Intragenomic mutational heterogeneity: structural and functional insights from gene evolution

Publication typeJournal Article
Publication date2025-05-05
scimago Q1
wos Q1
SJR3.928
CiteScore23.6
Impact factor16.3
ISSN01689525, 13624555
Abstract
Variation of mutation rates between species has been documented over decades, but the variation between different regions of a genome has been less often discussed. Recent studies using high-quality sequence data have revealed previously unknown levels of intragenomic heterogeneity of mutation rates and their association with other structural and functional features of DNA sequences. This article reviews accumulating evidence of this intragenomic heterogeneity and speculates its cause and influence on organismal phenotypes.
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Hara Y. et al. Intragenomic mutational heterogeneity: structural and functional insights from gene evolution // Trends in Genetics. 2025. Vol. 41. No. 11. pp. 974-983.
GOST all authors (up to 50) Copy
Hara Y., Kuraku S. Intragenomic mutational heterogeneity: structural and functional insights from gene evolution // Trends in Genetics. 2025. Vol. 41. No. 11. pp. 974-983.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/j.tig.2025.03.007
UR - https://linkinghub.elsevier.com/retrieve/pii/S0168952525000757
TI - Intragenomic mutational heterogeneity: structural and functional insights from gene evolution
T2 - Trends in Genetics
AU - Hara, Yuichiro
AU - Kuraku, Shigehiro
PY - 2025
DA - 2025/05/05
PB - Elsevier
SP - 974-983
IS - 11
VL - 41
SN - 0168-9525
SN - 1362-4555
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2025_Hara,
author = {Yuichiro Hara and Shigehiro Kuraku},
title = {Intragenomic mutational heterogeneity: structural and functional insights from gene evolution},
journal = {Trends in Genetics},
year = {2025},
volume = {41},
publisher = {Elsevier},
month = {may},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0168952525000757},
number = {11},
pages = {974--983},
doi = {10.1016/j.tig.2025.03.007}
}
MLA
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MLA Copy
Hara, Yuichiro, et al. “Intragenomic mutational heterogeneity: structural and functional insights from gene evolution.” Trends in Genetics, vol. 41, no. 11, May. 2025, pp. 974-983. https://linkinghub.elsevier.com/retrieve/pii/S0168952525000757.