Gender difference and BMDL exploration of developmental immunotoxicity induced by early-life low-dose exposure to 4-nonylphenol in Wistar rats
Jiuming Yan
1, 2, 3
,
Xiaoya Wang
1, 3
,
JingHua Xie
4
,
Liang Wang
1, 3
,
Qijie Wei
1, 3
,
Zhenchao Jia
5
,
Jinyao Chen
1, 3
2
3
Food Safety Monitoring and Risk Assessment Key Laboratory of Sichuan Province, Chengdu 610041, China
|
4
The Third Hospital of Mianyang (Sichuan Mental Health Center), China
|
Publication type: Journal Article
Publication date: 2025-05-01
scimago Q1
wos Q1
SJR: 1.106
CiteScore: 8.9
Impact factor: 4.6
ISSN: 0300483X, 18793185
Abstract
BackgroundNonylphenol (NP) is a widespread environmental endocrine disruptor with potential developmental immunotoxicity. The present study aimed to investigate the gender-specific developmental immunotoxic effects of early-life exposure to low doses of 4-nonylphenol (4-NP) on Wistar rats and the corresponding thresholds.
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Yan J. et al. Gender difference and BMDL exploration of developmental immunotoxicity induced by early-life low-dose exposure to 4-nonylphenol in Wistar rats // Toxicology. 2025. Vol. 513. p. 154085.
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Yan J., Wang X., Xie J., Wang L., Wei Q., Jia Z., Chen J. Gender difference and BMDL exploration of developmental immunotoxicity induced by early-life low-dose exposure to 4-nonylphenol in Wistar rats // Toxicology. 2025. Vol. 513. p. 154085.
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TY - JOUR
DO - 10.1016/j.tox.2025.154085
UR - https://linkinghub.elsevier.com/retrieve/pii/S0300483X25000411
TI - Gender difference and BMDL exploration of developmental immunotoxicity induced by early-life low-dose exposure to 4-nonylphenol in Wistar rats
T2 - Toxicology
AU - Yan, Jiuming
AU - Wang, Xiaoya
AU - Xie, JingHua
AU - Wang, Liang
AU - Wei, Qijie
AU - Jia, Zhenchao
AU - Chen, Jinyao
PY - 2025
DA - 2025/05/01
PB - Elsevier
SP - 154085
VL - 513
SN - 0300-483X
SN - 1879-3185
ER -
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@article{2025_Yan,
author = {Jiuming Yan and Xiaoya Wang and JingHua Xie and Liang Wang and Qijie Wei and Zhenchao Jia and Jinyao Chen},
title = {Gender difference and BMDL exploration of developmental immunotoxicity induced by early-life low-dose exposure to 4-nonylphenol in Wistar rats},
journal = {Toxicology},
year = {2025},
volume = {513},
publisher = {Elsevier},
month = {may},
url = {https://linkinghub.elsevier.com/retrieve/pii/S0300483X25000411},
pages = {154085},
doi = {10.1016/j.tox.2025.154085}
}