Elsevier
Urologic Oncology: Seminars and Original Investigations
,  volume 43 ,  issue 3 ,  pages 190.e11-190.e20

Bladder cancer associated with elevated heavy metals: Investigation of probable carcinogenic pathways through mitochondrial dysfunction, oxidative stress and mitogen-activated protein kinase

Bedeir Ali-El-Dein 1, 2
, 
Mahmoud Abdelgawad 3
, 
Mahmoud H Abdelgawad 4
, 
Tarek Mohamed 5
, 
Mona Abdel-Rahim 2
, 
M. Abdelrahim 5
, 
Manar E. Elkady 2, 5
, 
Hazem H Saleh 2, 5
, 
Mahmoud M Zakaria 2
, 
Mahmoud Zakaria 5
, 
Heba H Tarabay 2, 5
, 
Mahmoud Laymon 5
, 
Ahmed Mosbah 2, 5
, 
Arnolf Stenzl 6, 7
, 
Arnulf Stenzl 6
1
 
2
 
3
 
Toshka Urology and Endoscopy Center, Mansoura, Egypt | 
4
 
Toshka Urology and Endoscopy center, Mansoura, Egypt. | 
5
 
6
 
7
 
Publication type: Journal Article
Publication date: 2025-03-01
Elsevier
scimago Q1
wos Q2
SJR: 0.855
CiteScore: 5.0
Impact factor: 2.3
ISSN: 10781439, 18732496
Abstract
ObjectiveCarcinogenic mechanisms of heavy metals/ trace elements (HMTE) in bladder cancer (BC) are exactly unknown. Mitochondrial dysfunction (MD), oxidative stress (OS), and mitogen-activated protein kinases (MAPK) are probable carcinogenic mechanisms. The purpose is to investigate probable carcinogenic pathways of HMTE in BC using six MD genes, seven OS markers, and p38-MAPK.
Found 
Found 

Top-30

Journals

1
Toxicology Reports
Toxicology Reports, 1, 100%
Toxicology Reports
1 publication, 100%
1

Publishers

1
Elsevier
Elsevier, 1, 100%
Elsevier
1 publication, 100%
1
  • We do not take into account publications without a DOI.
  • Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
1
Share
Cite this
GOST |
Cite this
GOST Copy
Ali-El-Dein B. et al. Bladder cancer associated with elevated heavy metals: Investigation of probable carcinogenic pathways through mitochondrial dysfunction, oxidative stress and mitogen-activated protein kinase // Urologic Oncology: Seminars and Original Investigations. 2025. Vol. 43. No. 3. p. 190.e11-190.e20.
GOST all authors (up to 50) Copy
Ali-El-Dein B., Abdelgawad M., Abdelgawad M. H., Mohamed T., Abdel-Rahim M., Abdelrahim M., Elkady M. E., Saleh H. H., Zakaria M. M., Zakaria M., Tarabay H. H., Laymon M., Mosbah A., Stenzl A., Stenzl A. Bladder cancer associated with elevated heavy metals: Investigation of probable carcinogenic pathways through mitochondrial dysfunction, oxidative stress and mitogen-activated protein kinase // Urologic Oncology: Seminars and Original Investigations. 2025. Vol. 43. No. 3. p. 190.e11-190.e20.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/j.urolonc.2024.09.009
UR - https://linkinghub.elsevier.com/retrieve/pii/S1078143924006501
TI - Bladder cancer associated with elevated heavy metals: Investigation of probable carcinogenic pathways through mitochondrial dysfunction, oxidative stress and mitogen-activated protein kinase
T2 - Urologic Oncology: Seminars and Original Investigations
AU - Ali-El-Dein, Bedeir
AU - Abdelgawad, Mahmoud
AU - Abdelgawad, Mahmoud H
AU - Mohamed, Tarek
AU - Abdel-Rahim, Mona
AU - Abdelrahim, M.
AU - Elkady, Manar E.
AU - Saleh, Hazem H
AU - Zakaria, Mahmoud M
AU - Zakaria, Mahmoud
AU - Tarabay, Heba H
AU - Laymon, Mahmoud
AU - Mosbah, Ahmed
AU - Stenzl, Arnolf
AU - Stenzl, Arnulf
PY - 2025
DA - 2025/03/01
PB - Elsevier
SP - 190.e11-190.e20
IS - 3
VL - 43
PMID - 39379209
SN - 1078-1439
SN - 1873-2496
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2025_Ali-El-Dein,
author = {Bedeir Ali-El-Dein and Mahmoud Abdelgawad and Mahmoud H Abdelgawad and Tarek Mohamed and Mona Abdel-Rahim and M. Abdelrahim and Manar E. Elkady and Hazem H Saleh and Mahmoud M Zakaria and Mahmoud Zakaria and Heba H Tarabay and Mahmoud Laymon and Ahmed Mosbah and Arnolf Stenzl and Arnulf Stenzl},
title = {Bladder cancer associated with elevated heavy metals: Investigation of probable carcinogenic pathways through mitochondrial dysfunction, oxidative stress and mitogen-activated protein kinase},
journal = {Urologic Oncology: Seminars and Original Investigations},
year = {2025},
volume = {43},
publisher = {Elsevier},
month = {mar},
url = {https://linkinghub.elsevier.com/retrieve/pii/S1078143924006501},
number = {3},
pages = {190.e11--190.e20},
doi = {10.1016/j.urolonc.2024.09.009}
}
MLA
Cite this
MLA Copy
Ali-El-Dein, Bedeir, et al. “Bladder cancer associated with elevated heavy metals: Investigation of probable carcinogenic pathways through mitochondrial dysfunction, oxidative stress and mitogen-activated protein kinase.” Urologic Oncology: Seminars and Original Investigations, vol. 43, no. 3, Mar. 2025, pp. 190.e11-190.e20. https://linkinghub.elsevier.com/retrieve/pii/S1078143924006501.