Study on direct benzoannelations of pyrrole and indole systems by domino reactions with 4,5-dicyanopyridazine
Тип публикации: Journal Article
Дата публикации: 2002-09-01
scimago Q3
wos Q2
БС2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Краткое описание
The title pyridazine 1 was found to undergo hetero Diels–Alder [4+2] cycloadditions on the C(2)–C(3) double bond of pyrrole and indole systems; spontaneous loss of nitrogen from the primary adducts, followed by oxidation processes, afforded the corresponding fully aromatic benzoannelated skeletons in modest and reasonable yields, respectively. Competitive attacks of the same systems at the strongly electrophilic C-4 carbon of 1 , leading to substitution products, were evidenced.
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Giomi D., Cecchi M. Study on direct benzoannelations of pyrrole and indole systems by domino reactions with 4,5-dicyanopyridazine // Tetrahedron. 2002. Vol. 58. No. 40. pp. 8067-8071.
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Giomi D., Cecchi M. Study on direct benzoannelations of pyrrole and indole systems by domino reactions with 4,5-dicyanopyridazine // Tetrahedron. 2002. Vol. 58. No. 40. pp. 8067-8071.
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TY - JOUR
DO - 10.1016/s0040-4020(02)00958-4
UR - https://doi.org/10.1016/s0040-4020(02)00958-4
TI - Study on direct benzoannelations of pyrrole and indole systems by domino reactions with 4,5-dicyanopyridazine
T2 - Tetrahedron
AU - Giomi, Donatella
AU - Cecchi, Marco
PY - 2002
DA - 2002/09/01
PB - Elsevier
SP - 8067-8071
IS - 40
VL - 58
SN - 0040-4020
SN - 1464-5416
ER -
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@article{2002_Giomi,
author = {Donatella Giomi and Marco Cecchi},
title = {Study on direct benzoannelations of pyrrole and indole systems by domino reactions with 4,5-dicyanopyridazine},
journal = {Tetrahedron},
year = {2002},
volume = {58},
publisher = {Elsevier},
month = {sep},
url = {https://doi.org/10.1016/s0040-4020(02)00958-4},
number = {40},
pages = {8067--8071},
doi = {10.1016/s0040-4020(02)00958-4}
}
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MLA
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Giomi, Donatella, and Marco Cecchi. “Study on direct benzoannelations of pyrrole and indole systems by domino reactions with 4,5-dicyanopyridazine.” Tetrahedron, vol. 58, no. 40, Sep. 2002, pp. 8067-8071. https://doi.org/10.1016/s0040-4020(02)00958-4.