Tetrahedron, volume 54, issue 22, pages 6147-6158
Reactions of chloromethyl aryl sulfones carbanions with anthraquinone derivatives
Mieczysz Shtslslaw Ma̧kosza
1
,
Shamil Nizamov
1
,
Zofia Urbańczyk-Lipkowska
1
1
Institute of Organic Chemistry Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw (Poland).
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Publication type: Journal Article
Publication date: 1998-05-01
Journal:
Tetrahedron
scimago Q3
wos Q2
SJR: 0.406
CiteScore: 3.9
Impact factor: 2.1
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
Carbanions of chloromethyl phenyl sulfone and chloromethyl p -tolyl sulfone react with anthraquinone containing electrondonating substituents in two major ways: vicarious nucleophilic substitution (VNS) of hydrogen and addition to the carbonyl group. The reaction course depends on electrondonating effects of these substituents-strong electron donors promote the VNS reaction. Graphic
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