Tetrahedron, volume 54, issue 22, pages 6147-6158

Reactions of chloromethyl aryl sulfones carbanions with anthraquinone derivatives

Mieczysz Shtslslaw Ma̧kosza 1
Shamil Nizamov 1
Zofia Urbańczyk-Lipkowska 1
1
 
Institute of Organic Chemistry Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw (Poland).
Publication typeJournal Article
Publication date1998-05-01
Journal: Tetrahedron
scimago Q3
wos Q2
SJR0.406
CiteScore3.9
Impact factor2.1
ISSN00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
Carbanions of chloromethyl phenyl sulfone and chloromethyl p -tolyl sulfone react with anthraquinone containing electrondonating substituents in two major ways: vicarious nucleophilic substitution (VNS) of hydrogen and addition to the carbonyl group. The reaction course depends on electrondonating effects of these substituents-strong electron donors promote the VNS reaction. Graphic

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