Synthesis of Trifluoromethylpyrroles and Related Heterocycles from 4-Ethyloxy-1,1,1-trifluorobut-3-ene-2-one
Publication type: Journal Article
Publication date: 2000-09-01
scimago Q3
wos Q2
SJR: 0.426
CiteScore: 4.1
Impact factor: 2.2
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
Syntheses of intermediate 4-dialkylamino-1,1,1-trifluorobut-3-ene-2-ones are described from 4-ethyloxy-1,1,1-trifluorobut-3-ene-2-one and α-aminoacids. In subsequent cyclisations pyrroles and other bicyclic heteroaromatics having trifluoromethyl substitution are obtained either by simple dehydration or with concomitant decarboxylation.
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GOST
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Andrew R. J., Mellor J. M. Synthesis of Trifluoromethylpyrroles and Related Heterocycles from 4-Ethyloxy-1,1,1-trifluorobut-3-ene-2-one // Tetrahedron. 2000. Vol. 56. No. 37. pp. 7267-7272.
GOST all authors (up to 50)
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Andrew R. J., Mellor J. M. Synthesis of Trifluoromethylpyrroles and Related Heterocycles from 4-Ethyloxy-1,1,1-trifluorobut-3-ene-2-one // Tetrahedron. 2000. Vol. 56. No. 37. pp. 7267-7272.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/s0040-4020(00)00598-6
UR - https://doi.org/10.1016/s0040-4020(00)00598-6
TI - Synthesis of Trifluoromethylpyrroles and Related Heterocycles from 4-Ethyloxy-1,1,1-trifluorobut-3-ene-2-one
T2 - Tetrahedron
AU - Andrew, Rebecca J
AU - Mellor, John M
PY - 2000
DA - 2000/09/01
PB - Elsevier
SP - 7267-7272
IS - 37
VL - 56
SN - 0040-4020
SN - 1464-5416
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2000_Andrew,
author = {Rebecca J Andrew and John M Mellor},
title = {Synthesis of Trifluoromethylpyrroles and Related Heterocycles from 4-Ethyloxy-1,1,1-trifluorobut-3-ene-2-one},
journal = {Tetrahedron},
year = {2000},
volume = {56},
publisher = {Elsevier},
month = {sep},
url = {https://doi.org/10.1016/s0040-4020(00)00598-6},
number = {37},
pages = {7267--7272},
doi = {10.1016/s0040-4020(00)00598-6}
}
Cite this
MLA
Copy
Andrew, Rebecca J., and John M Mellor. “Synthesis of Trifluoromethylpyrroles and Related Heterocycles from 4-Ethyloxy-1,1,1-trifluorobut-3-ene-2-one.” Tetrahedron, vol. 56, no. 37, Sep. 2000, pp. 7267-7272. https://doi.org/10.1016/s0040-4020(00)00598-6.