volume 38 issue 16 pages 2795-2798

A new synthesis of 8-methylpsoralen utilizing a palladium-copper catalyzed reaction to generate the furan ring and thus allowing for the generation of novel analogs in the 5′-position

Publication typeJournal Article
Publication date1997-04-01
scimago Q3
wos Q3
SJR0.334
CiteScore3.2
Impact factor1.5
ISSN00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
A rapid synthesis of 8-methylpsoralen is reported that utilizes a palladium-copper catalyzed reaction to generate the furan ring. Since 8-methylpsoralen is considered one of the most photodynamic methylpsoralens known and given the fact that psoralens in general have been shown to have medicinal value against bacteria and viruses, this synthesis allows for the availability to generate new derivatives by supplying a handle in the 5′-position. 1 A new synthesis of 8-methylpsoralen that allows for the modification of the 5′-position in the psoralen ring system.
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Aquila B. M. A new synthesis of 8-methylpsoralen utilizing a palladium-copper catalyzed reaction to generate the furan ring and thus allowing for the generation of novel analogs in the 5′-position // Tetrahedron Letters. 1997. Vol. 38. No. 16. pp. 2795-2798.
GOST all authors (up to 50) Copy
Aquila B. M. A new synthesis of 8-methylpsoralen utilizing a palladium-copper catalyzed reaction to generate the furan ring and thus allowing for the generation of novel analogs in the 5′-position // Tetrahedron Letters. 1997. Vol. 38. No. 16. pp. 2795-2798.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1016/s0040-4039(97)00509-1
UR - https://doi.org/10.1016/s0040-4039(97)00509-1
TI - A new synthesis of 8-methylpsoralen utilizing a palladium-copper catalyzed reaction to generate the furan ring and thus allowing for the generation of novel analogs in the 5′-position
T2 - Tetrahedron Letters
AU - Aquila, Brian M
PY - 1997
DA - 1997/04/01
PB - Elsevier
SP - 2795-2798
IS - 16
VL - 38
SN - 0040-4039
SN - 1873-3581
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{1997_Aquila,
author = {Brian M Aquila},
title = {A new synthesis of 8-methylpsoralen utilizing a palladium-copper catalyzed reaction to generate the furan ring and thus allowing for the generation of novel analogs in the 5′-position},
journal = {Tetrahedron Letters},
year = {1997},
volume = {38},
publisher = {Elsevier},
month = {apr},
url = {https://doi.org/10.1016/s0040-4039(97)00509-1},
number = {16},
pages = {2795--2798},
doi = {10.1016/s0040-4039(97)00509-1}
}
MLA
Cite this
MLA Copy
Aquila, Brian M.. “A new synthesis of 8-methylpsoralen utilizing a palladium-copper catalyzed reaction to generate the furan ring and thus allowing for the generation of novel analogs in the 5′-position.” Tetrahedron Letters, vol. 38, no. 16, Apr. 1997, pp. 2795-2798. https://doi.org/10.1016/s0040-4039(97)00509-1.