Cancer Treatment Reviews, volume 29, issue 6, pages 515-523

Classification of anticancer drugs—a new system based on therapeutic targets

Enrique Espinosa 1
Pilar Zamora 1
Jaime Feliu 1
Manuel González-Barón 1
1
 
Servicio de Oncologı́a Médica, Hospital La Paz, Madrid, Spain
Publication typeJournal Article
Publication date2003-12-01
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor11.8
ISSN03057372
Oncology
General Medicine
Radiology, Nuclear Medicine and imaging
Abstract
The arrival of a great number of new antineoplastic agents has made it necessary to reclassify all of them. Anticancer drugs may act at different levels: cancer cells, endothelium, extracellular matrix, the immune system or host cells. The tumour cell can be targeted at the DNA, RNA or protein level. Most classical chemotherapeutic agents interact with tumour DNA, whereas monoclonal antibodies and small molecules are directed against proteins. The endothelium and extracellular matrix may be affected also by specific antibodies and small molecules.

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GOST |
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GOST Copy
Espinosa E. et al. Classification of anticancer drugs—a new system based on therapeutic targets // Cancer Treatment Reviews. 2003. Vol. 29. No. 6. pp. 515-523.
GOST all authors (up to 50) Copy
Espinosa E., Zamora P., Feliu J., González-Barón M. Classification of anticancer drugs—a new system based on therapeutic targets // Cancer Treatment Reviews. 2003. Vol. 29. No. 6. pp. 515-523.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1016/s0305-7372(03)00116-6
UR - https://doi.org/10.1016/s0305-7372(03)00116-6
TI - Classification of anticancer drugs—a new system based on therapeutic targets
T2 - Cancer Treatment Reviews
AU - Espinosa, Enrique
AU - Zamora, Pilar
AU - Feliu, Jaime
AU - González-Barón, Manuel
PY - 2003
DA - 2003/12/01
PB - Elsevier
SP - 515-523
IS - 6
VL - 29
SN - 0305-7372
ER -
BibTex |
Cite this
BibTex Copy
@article{2003_Espinosa,
author = {Enrique Espinosa and Pilar Zamora and Jaime Feliu and Manuel González-Barón},
title = {Classification of anticancer drugs—a new system based on therapeutic targets},
journal = {Cancer Treatment Reviews},
year = {2003},
volume = {29},
publisher = {Elsevier},
month = {dec},
url = {https://doi.org/10.1016/s0305-7372(03)00116-6},
number = {6},
pages = {515--523},
doi = {10.1016/s0305-7372(03)00116-6}
}
MLA
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MLA Copy
Espinosa, Enrique, et al. “Classification of anticancer drugs—a new system based on therapeutic targets.” Cancer Treatment Reviews, vol. 29, no. 6, Dec. 2003, pp. 515-523. https://doi.org/10.1016/s0305-7372(03)00116-6.
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