Investigation of the chemical equivalence of the trypanocidal products, Samorin® and Veridium®
Publication type: Journal Article
Publication date: 1999-10-01
scimago Q2
wos Q2
SJR: 0.628
CiteScore: 6.4
Impact factor: 3.1
ISSN: 07317085, 1873264X
PubMed ID:
10701907
Drug Discovery
Spectroscopy
Pharmaceutical Science
Clinical Biochemistry
Analytical Chemistry
Abstract
A procedure for the evaluation of chemical equivalence of proprietary formulations of isometamidium is described. The method combines the analysis of the principal component (isometamidium), HPLC profiling of related substances and determination of the inorganic impurity, ammonium chloride, using a modification of the Berthelot (Indophenol) reaction. Application of these procedures to analyses of commercially available sachets from four different batches of Samorin and four different batches of Veridium has demonstrated that there are marked qualitative and quantitative differences between batches from these two sources. Whilst Samorin samples showed inter-batch consistency of composition, there was considerable inter-batch variation between the samples of Veridium.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
|
|
|
Trends in Parasitology
1 publication, 12.5%
|
|
|
Acta Tropica
1 publication, 12.5%
|
|
|
Tetrahedron Letters
1 publication, 12.5%
|
|
|
Analytical and Bioanalytical Chemistry
1 publication, 12.5%
|
|
|
Journal of Pharmaceutical and Biomedical Analysis
1 publication, 12.5%
|
|
|
Veterinary Parasitology
1 publication, 12.5%
|
|
|
Chemistry - A European Journal
1 publication, 12.5%
|
|
|
Veterinary Parasitology: Regional Studies and Reports
1 publication, 12.5%
|
|
|
1
|
Publishers
|
1
2
3
4
5
6
|
|
|
Elsevier
6 publications, 75%
|
|
|
Springer Nature
1 publication, 12.5%
|
|
|
Wiley
1 publication, 12.5%
|
|
|
1
2
3
4
5
6
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
8
Total citations:
8
Citations from 2024:
1
(12.5%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Tettey J. et al. Investigation of the chemical equivalence of the trypanocidal products, Samorin® and Veridium® // Journal of Pharmaceutical and Biomedical Analysis. 1999. Vol. 21. No. 1. pp. 1-7.
GOST all authors (up to 50)
Copy
Tettey J., SKELLERN G. G., Grant M. B., Midgley J. M. Investigation of the chemical equivalence of the trypanocidal products, Samorin® and Veridium® // Journal of Pharmaceutical and Biomedical Analysis. 1999. Vol. 21. No. 1. pp. 1-7.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/s0731-7085(99)00110-7
UR - https://doi.org/10.1016/s0731-7085(99)00110-7
TI - Investigation of the chemical equivalence of the trypanocidal products, Samorin® and Veridium®
T2 - Journal of Pharmaceutical and Biomedical Analysis
AU - Tettey, J.N.A
AU - SKELLERN, G. G.
AU - Grant, Maria B.
AU - Midgley, J M
PY - 1999
DA - 1999/10/01
PB - Elsevier
SP - 1-7
IS - 1
VL - 21
PMID - 10701907
SN - 0731-7085
SN - 1873-264X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1999_Tettey,
author = {J.N.A Tettey and G. G. SKELLERN and Maria B. Grant and J M Midgley},
title = {Investigation of the chemical equivalence of the trypanocidal products, Samorin® and Veridium®},
journal = {Journal of Pharmaceutical and Biomedical Analysis},
year = {1999},
volume = {21},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/s0731-7085(99)00110-7},
number = {1},
pages = {1--7},
doi = {10.1016/s0731-7085(99)00110-7}
}
Cite this
MLA
Copy
Tettey, J.N.A, et al. “Investigation of the chemical equivalence of the trypanocidal products, Samorin® and Veridium®.” Journal of Pharmaceutical and Biomedical Analysis, vol. 21, no. 1, Oct. 1999, pp. 1-7. https://doi.org/10.1016/s0731-7085(99)00110-7.