Mechanisms by which Thiazolidinediones Enhance Insulin Action
Publication type: Journal Article
Publication date: 1999-01-01
scimago Q1
wos Q1
SJR: 3.485
CiteScore: 21.2
Impact factor: 12.6
ISSN: 10432760, 18793061
PubMed ID:
10322388
Endocrinology
Endocrinology, Diabetes and Metabolism
Abstract
Thiazolidinediones (TZDs) are an exciting new class of insulin-sensitizing drugs being used currently for the treatment of non-insulin-dependent diabetes mellitus. The molecular target of these compounds is thought to be the nuclear hormone receptor, peroxisome proliferator-activated receptor gamma (PPARgamma). PPARgamma is expressed predominantly in adipose tissue, yet a major site of TZD-responsive glucose disposal is skeletal muscle. Potential explanations for this paradox are discussed in this review.
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70
Total citations:
70
Citations from 2024:
4
(5.72%)
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MLA
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GOST
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Reginato M. J., Lazar M. A. Mechanisms by which Thiazolidinediones Enhance Insulin Action // Trends in Endocrinology and Metabolism. 1999. Vol. 10. No. 1. pp. 9-13.
GOST all authors (up to 50)
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Reginato M. J., Lazar M. A. Mechanisms by which Thiazolidinediones Enhance Insulin Action // Trends in Endocrinology and Metabolism. 1999. Vol. 10. No. 1. pp. 9-13.
Cite this
RIS
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TY - JOUR
DO - 10.1016/s1043-2760(98)00110-6
UR - https://doi.org/10.1016/s1043-2760(98)00110-6
TI - Mechanisms by which Thiazolidinediones Enhance Insulin Action
T2 - Trends in Endocrinology and Metabolism
AU - Reginato, Mauricio J.
AU - Lazar, M. A.
PY - 1999
DA - 1999/01/01
PB - Elsevier
SP - 9-13
IS - 1
VL - 10
PMID - 10322388
SN - 1043-2760
SN - 1879-3061
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1999_Reginato,
author = {Mauricio J. Reginato and M. A. Lazar},
title = {Mechanisms by which Thiazolidinediones Enhance Insulin Action},
journal = {Trends in Endocrinology and Metabolism},
year = {1999},
volume = {10},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/s1043-2760(98)00110-6},
number = {1},
pages = {9--13},
doi = {10.1016/s1043-2760(98)00110-6}
}
Cite this
MLA
Copy
Reginato, Mauricio J., and M. A. Lazar. “Mechanisms by which Thiazolidinediones Enhance Insulin Action.” Trends in Endocrinology and Metabolism, vol. 10, no. 1, Jan. 1999, pp. 9-13. https://doi.org/10.1016/s1043-2760(98)00110-6.