Il Farmaco

, том 57 , издание 2 , страницы 171-174

Synthesis and antimicrobial activity of some new hydrazones of 4-fluorobenzoic acid hydrazide and 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines

Тип публикации: Journal Article

Дата публикации: 2002-02-01

Elsevier

Il Farmaco

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ISSN: 0014827X

DOI: 10.1016/S0014-827X(01)01192-2

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PubMed ID: 11902660

Drug Discovery

Pharmaceutical Science

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A series of hydrazide hydrazones and 1,3,4-oxadiazolines of 4-fluorobenzoic acid hydrazide were prepared and evaluated as potential antimicrobial agents and were tested for their antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. From these compounds, 4-fluorobenzoic acid[(5-nitro-2-furanyl)methylene]hydrazide (1a) showed equal activity with ceftriaxone against S. aureus. In addition, the MIC values of compounds 1c, 1d and 2a for the same strain were in the range of those reported for ceftriaxone according to NCCLS 1997.

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Rollas S., Gulerman N., Erdeniz H. Synthesis and antimicrobial activity of some new hydrazones of 4-fluorobenzoic acid hydrazide and 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines // Il Farmaco. 2002. Vol. 57. No. 2. pp. 171-174.

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TY - JOUR

DO - 10.1016/S0014-827X(01)01192-2

UR - https://doi.org/10.1016/S0014-827X(01)01192-2

TI - Synthesis and antimicrobial activity of some new hydrazones of 4-fluorobenzoic acid hydrazide and 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines

T2 - Il Farmaco

AU - Rollas, Sevim

AU - Gulerman, Nehir

AU - Erdeniz, Habibe

PY - 2002

DA - 2002/02/01

PB - Elsevier

SP - 171-174

IS - 2

VL - 57

PMID - 11902660

SN - 0014-827X

ER -

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@article{2002_Rollas,

author = {Sevim Rollas and Nehir Gulerman and Habibe Erdeniz},

title = {Synthesis and antimicrobial activity of some new hydrazones of 4-fluorobenzoic acid hydrazide and 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines},

journal = {Il Farmaco},

year = {2002},

volume = {57},

publisher = {Elsevier},

month = {feb},

url = {https://doi.org/10.1016/S0014-827X(01)01192-2},

number = {2},

pages = {171--174},

doi = {10.1016/S0014-827X(01)01192-2}

}

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Rollas, Sevim, et al. “Synthesis and antimicrobial activity of some new hydrazones of 4-fluorobenzoic acid hydrazide and 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines.” Il Farmaco, vol. 57, no. 2, Feb. 2002, pp. 171-174. https://doi.org/10.1016/S0014-827X(01)01192-2.

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Издатель

Elsevier

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Il Farmaco

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ISSN

0014827X (Print)