Tetrahedron

, volume 58 , issue 49 , pages 9859-9863

A novel synthesis of 3(R)-HETE, 3(R)-HTDE and enzymatic synthesis of 3(R),15(S)-DiHETE

Natalia V. Groza ¹

Igor Ivanov ¹

Stepan G. Romanov ¹

Galina I. Myagkova ¹

Santosh NIGAM ²

Hide authors affiliations Show authors affiliations: 2 affiliations

M.V. Lomonosov State Academy of Fine Chemical Technology, Pr. Vernadskogo 86, 119571 Moscow, Russian Federation |

Department of Gynecology, Eicosanoid Research Division, University Medical Centre Benjamin Franklin, Free University Berlin, Hindenburgdamm 30, D-12200 Berlin, Germany |

Publication type: Journal Article

Publication date: 2002-12-01

Elsevier

Tetrahedron

scimago Q3

wos Q2

SJR: 0.426

CiteScore: 4.1

Impact factor: 2.2

ISSN: 00404020, 14645416

DOI: 10.1016/S0040-4020(02)01289-9

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Organic Chemistry

Drug Discovery

Biochemistry

Abstract

3(R)-HETE and 3(R)-HTDE were prepared by cross-coupling of methyl 3(R)-hydroxyhex-5-ynoate either with 1-bromo-2,5,8-tetradecatriyne or 1-bromo-2-octyne followed by catalytic hydrogenation of the skipped triple bonds formed using Lindlar's catalyst. Enzymatic synthesis of 3(R),15(S)-DiHETE was accomplished by soybean LOX-1 using 3(R)-HETE as a substrate.

Found

1 citation

Maslov Mikhail

DSc in Chemistry, associate professor

89 publications, 879 citations, 13 reviews

h-index: 15

MIREA — Russian Technological University

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GOST |

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GOST Copy

Romanov S. G. et al. A novel synthesis of 3(R)-HETE, 3(R)-HTDE and enzymatic synthesis of 3(R),15(S)-DiHETE // Tetrahedron. 2002. Vol. 58. No. 49. pp. 9859-9863.

GOST all authors (up to 50) Copy

Groza N. V., Ivanov I., Romanov S. G., Myagkova G. I., NIGAM S. A novel synthesis of 3(R)-HETE, 3(R)-HTDE and enzymatic synthesis of 3(R),15(S)-DiHETE // Tetrahedron. 2002. Vol. 58. No. 49. pp. 9859-9863.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1016/S0040-4020(02)01289-9

UR - https://linkinghub.elsevier.com/retrieve/pii/S0040402002012899

TI - A novel synthesis of 3(R)-HETE, 3(R)-HTDE and enzymatic synthesis of 3(R),15(S)-DiHETE

T2 - Tetrahedron

AU - Groza, Natalia V.

AU - Ivanov, Igor

AU - Romanov, Stepan G.

AU - Myagkova, Galina I.

AU - NIGAM, Santosh

PY - 2002

DA - 2002/12/01

PB - Elsevier

SP - 9859-9863

IS - 49

VL - 58

SN - 0040-4020

SN - 1464-5416

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2002_Romanov,

author = {Natalia V. Groza and Igor Ivanov and Stepan G. Romanov and Galina I. Myagkova and Santosh NIGAM},

title = {A novel synthesis of 3(R)-HETE, 3(R)-HTDE and enzymatic synthesis of 3(R),15(S)-DiHETE},

journal = {Tetrahedron},

year = {2002},

volume = {58},

publisher = {Elsevier},

month = {dec},

url = {https://linkinghub.elsevier.com/retrieve/pii/S0040402002012899},

number = {49},

pages = {9859--9863},

doi = {10.1016/S0040-4020(02)01289-9}

}

MLA

Cite this

MLA Copy

Romanov, Stepan G., et al. “A novel synthesis of 3(R)-HETE, 3(R)-HTDE and enzymatic synthesis of 3(R),15(S)-DiHETE.” Tetrahedron, vol. 58, no. 49, Dec. 2002, pp. 9859-9863. https://linkinghub.elsevier.com/retrieve/pii/S0040402002012899.

Publisher

Elsevier

Journal

Tetrahedron

scimago Q3

wos Q2

SJR

0.426

CiteScore

4.1

Impact factor

2.2

ISSN

00404020 (Print)

14645416 (Electronic)

Profiles

Igor V Ivanov