,  том 57 ,  издание 40 ,  страницы 8573-8580

Synthesis of 4-(trifluoromethyl)isoquinolines. Influence of trifluoromethyl group on the Pictet–Gams ring closure reaction

Тип публикации: Journal Article
Дата публикации: 2001-10-01
SCImago Q3
WOS Q3
БС2
SJR: 0.36
CiteScore: 3.7
Impact factor: 2.1
ISSN: 00404020, 14645416
Organic Chemistry
Drug Discovery
Biochemistry
Краткое описание
Treatment of N -acyl-2-methoxy-2-(trifluoromethyl)arylethylamines under Pictet–Gams conditions afforded 4-methoxy-4-trifluoromethyl-3,4-dihydroisoquinolines which were aromatised by base catalysed methanol elimination. Earlier we described the synthesis of 2-oxazolines by conducting the Pictet–Gams sequence with N -acyl-2-hydroxy-2-(trifluoromethyl)arylethylamines. The operation of these two pathways is explained by the influence of the trifluoromethyl group.
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ГОСТ |
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Poszávácz L., Simig G. Synthesis of 4-(trifluoromethyl)isoquinolines. Influence of trifluoromethyl group on the Pictet–Gams ring closure reaction // Tetrahedron. 2001. Vol. 57. No. 40. pp. 8573-8580.
ГОСТ со всеми авторами (до 50) Скопировать
Poszávácz L., Simig G. Synthesis of 4-(trifluoromethyl)isoquinolines. Influence of trifluoromethyl group on the Pictet–Gams ring closure reaction // Tetrahedron. 2001. Vol. 57. No. 40. pp. 8573-8580.
RIS |
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TY - JOUR
DO - 10.1016/S0040-4020(01)00836-5
UR - https://doi.org/10.1016/S0040-4020(01)00836-5
TI - Synthesis of 4-(trifluoromethyl)isoquinolines. Influence of trifluoromethyl group on the Pictet–Gams ring closure reaction
T2 - Tetrahedron
AU - Poszávácz, László
AU - Simig, Gyula
PY - 2001
DA - 2001/10/01
PB - Elsevier
SP - 8573-8580
IS - 40
VL - 57
SN - 0040-4020
SN - 1464-5416
ER -
BibTex |
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BibTex (до 50 авторов) Скопировать
@article{2001_Poszávácz,
author = {László Poszávácz and Gyula Simig},
title = {Synthesis of 4-(trifluoromethyl)isoquinolines. Influence of trifluoromethyl group on the Pictet–Gams ring closure reaction},
journal = {Tetrahedron},
year = {2001},
volume = {57},
publisher = {Elsevier},
month = {oct},
url = {https://doi.org/10.1016/S0040-4020(01)00836-5},
number = {40},
pages = {8573--8580},
doi = {10.1016/S0040-4020(01)00836-5}
}
MLA
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Poszávácz, László, and Gyula Simig. “Synthesis of 4-(trifluoromethyl)isoquinolines. Influence of trifluoromethyl group on the Pictet–Gams ring closure reaction.” Tetrahedron, vol. 57, no. 40, Oct. 2001, pp. 8573-8580. https://doi.org/10.1016/S0040-4020(01)00836-5.
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