Synthetic studies on (−)-tetrodotoxin (3) nitrogenation through overman rearrangement and guanidine ring formation
Minoru ISOBE
1
,
Yoshio FUKUDA
1
,
Toshio NISHIKAWA
1
,
Philippe Chabert
1
,
Takatoshi KAWAI
2, 3
,
TOSHIO GOTO
1
1
2
Eisai Co., Ltd. Tsukuba Research Laboratories, 1-3, Tokodai 5, Tsukuba, Ibaraki 300-26, Japan
|
Publication type: Journal Article
Publication date: 1990-01-01
scimago Q3
wos Q3
SJR: 0.334
CiteScore: 3.2
Impact factor: 1.5
ISSN: 00404039, 18733581
Organic Chemistry
Drug Discovery
Biochemistry
Abstract
The guanidinium part of tetrodotoxin was synthesized from a sugar derivative, levoglucosenone, in optically active form via Overman rearrangement as key step.
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38
Total citations:
38
Citations from 2025:
1
(2.63%)
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GOST
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ISOBE M. et al. Synthetic studies on (−)-tetrodotoxin (3) nitrogenation through overman rearrangement and guanidine ring formation // Tetrahedron Letters. 1990. Vol. 31. No. 23. pp. 3327-3330.
GOST all authors (up to 50)
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ISOBE M., FUKUDA Y., NISHIKAWA T., Chabert P., KAWAI T., GOTO T. Synthetic studies on (−)-tetrodotoxin (3) nitrogenation through overman rearrangement and guanidine ring formation // Tetrahedron Letters. 1990. Vol. 31. No. 23. pp. 3327-3330.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1016/S0040-4039(00)89056-5
UR - https://doi.org/10.1016/S0040-4039(00)89056-5
TI - Synthetic studies on (−)-tetrodotoxin (3) nitrogenation through overman rearrangement and guanidine ring formation
T2 - Tetrahedron Letters
AU - ISOBE, Minoru
AU - FUKUDA, Yoshio
AU - NISHIKAWA, Toshio
AU - Chabert, Philippe
AU - KAWAI, Takatoshi
AU - GOTO, TOSHIO
PY - 1990
DA - 1990/01/01
PB - Elsevier
SP - 3327-3330
IS - 23
VL - 31
SN - 0040-4039
SN - 1873-3581
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{1990_ISOBE,
author = {Minoru ISOBE and Yoshio FUKUDA and Toshio NISHIKAWA and Philippe Chabert and Takatoshi KAWAI and TOSHIO GOTO},
title = {Synthetic studies on (−)-tetrodotoxin (3) nitrogenation through overman rearrangement and guanidine ring formation},
journal = {Tetrahedron Letters},
year = {1990},
volume = {31},
publisher = {Elsevier},
month = {jan},
url = {https://doi.org/10.1016/S0040-4039(00)89056-5},
number = {23},
pages = {3327--3330},
doi = {10.1016/S0040-4039(00)89056-5}
}
Cite this
MLA
Copy
ISOBE, Minoru, et al. “Synthetic studies on (−)-tetrodotoxin (3) nitrogenation through overman rearrangement and guanidine ring formation.” Tetrahedron Letters, vol. 31, no. 23, Jan. 1990, pp. 3327-3330. https://doi.org/10.1016/S0040-4039(00)89056-5.