,
pages 95-146
Reactivity of Naphthyridines toward Nitrogen Nucleophiles
2
Instytut Chemii i Technologii Organieznej, Kraków, Poland
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Publication type: Book Chapter
Publication date: 1983-01-01
Abstract
This chapter summarizes the reactions that naphthyridines can undergo with KNH2/NH3. Naphthyridines are heterocyclic systems consisting of two fused aromatic rings, each one containing one nitrogen atom. The addition occurring between naphthyridines or substituted naphthyridines and azanucleophiles occurs by covalent amination of the parent naphthyridines and substituted naphthyridines. The chapter focusses on nucleophilic substitutions using nitrogen nucleophiles such as amide ions and liquid ammonia. Ring transformations that the naphthyridines can undergo are also discussed. The complex behavior of the naphthyridines toward the reagent (ipso, tele, and cine substitutions, as well as ring transformations) is also provided in a tabular form.
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Total citations:
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Citations from 2025:
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Van Der Plas H. C., Woźniak M., Van Den Haak H. J. W. Reactivity of Naphthyridines toward Nitrogen Nucleophiles // Advances in Heterocyclic Chemistry. 1983. pp. 95-146.
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Van Der Plas H. C., Woźniak M., Van Den Haak H. J. W. Reactivity of Naphthyridines toward Nitrogen Nucleophiles // Advances in Heterocyclic Chemistry. 1983. pp. 95-146.
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RIS
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TY - GENERIC
DO - 10.1016/S0065-2725(08)60052-5
UR - https://doi.org/10.1016/S0065-2725(08)60052-5
TI - Reactivity of Naphthyridines toward Nitrogen Nucleophiles
T2 - Advances in Heterocyclic Chemistry
AU - Van Der Plas, Henk C
AU - Woźniak, Marian
AU - Van Den Haak, Henk J W
PY - 1983
DA - 1983/01/01
PB - Elsevier
SP - 95-146
SN - 0065-2725
ER -
Cite this
BibTex (up to 50 authors)
Copy
@incollection{1983_Van Der Plas,
author = {Henk C Van Der Plas and Marian Woźniak and Henk J W Van Den Haak},
title = {Reactivity of Naphthyridines toward Nitrogen Nucleophiles},
publisher = {Elsevier},
year = {1983},
pages = {95--146},
month = {jan}
}